Acylation of biomolecules (eg, proteins and small molecules) is a process that occurs in cells
of all domains of life and has emerged as a critical mechanism for the control of many …

Epigenetic modifications represent mechanisms by which cells may effectively translate
multiple signaling inputs into phenotypic outputs. Recent research is revealing that redox …

We previously showed that Arabidopsis thaliana histone acetyltransferase TAF1/HAF2 is
required for the light regulation of growth and gene expression, and we show here that …

▪ Abstract Vitamin D is a secosteroid that is metabolically activated and degraded through
the actions of three cytochrome P450 hydroxylase enzymes. Bioactivation occurs through …

Gastric cancer is one of the most common malignant tumors worldwide. Due to its intricate
initiation and progression mechanisms, early detection and effective treatment of gastric …

Abstract PHYTOCHROME INTERACTING FACTOR3 (PIF3) is a key basic helix-loop-helix
transcription factor of Arabidopsis thaliana that negatively regulates light responses …

Many transcription factors regulate specific temporal-spatial events during cardiac
differentiation; however, the mechanisms that regulate such events are largely unknown …

Histone acetyltransferases and histone deacetylases regulate the acetylation of histones
and transcription factors, and in doing so have major roles in the control of cell fate. Many …

The post-translational modification of histones plays an important role in chromatin
regulation, a process that insures the fidelity of gene expression and other DNA …

The regulated production of several terminally differentiated cell types of the blood and
immune systems (haematopoiesis) has been the focus of many studies on cell-fate …