Emerging role of epigenetic mechanisms in alcohol addiction
TDM Berkel, SC Pandey - Alcoholism: Clinical and …, 2017 - Wiley Online Library
Alcohol use disorder (AUD) is a complex brain disorder with an array of persistent
behavioral and neurochemical manifestations. Both genetic and environmental factors are …
behavioral and neurochemical manifestations. Both genetic and environmental factors are …
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases
MV Simonini, LM Camargo, E Dong… - Proceedings of the …, 2006 - National Acad Sciences
The association of the histone deacetylase (HDAC) inhibitor valproate (VPA) with atypical
antipsychotics has become a frequent treatment strategy for schizophrenia and bipolar …
antipsychotics has become a frequent treatment strategy for schizophrenia and bipolar …
Recent advances in the development of polyamine analogues as antitumor agents
RA Casero Jr, PM Woster - Journal of medicinal chemistry, 2009 - ACS Publications
Since the publication of our previous Perspective dealing with polyamine drug discovery, 1
the field has undergone numerous changes. Most prominent among these changes, from a …
the field has undergone numerous changes. Most prominent among these changes, from a …
Modify the histone to win the battle: chromatin dynamics in plant–pathogen interactions
JS Ramirez-Prado, SJM Piquerez… - Frontiers in Plant …, 2018 - frontiersin.org
Relying on an immune system comes with a high energetic cost for plants. Defense
responses in these organisms are therefore highly regulated and fine-tuned, permitting them …
responses in these organisms are therefore highly regulated and fine-tuned, permitting them …
Epigenetic aberrations and cancer
M Ducasse, MA Brown - Molecular cancer, 2006 - Springer
Epigenetic aberrations and cancer | Molecular Cancer Skip to main content SpringerLink
Account Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Molecular …
Account Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Molecular …
The GCN5: its biological functions and therapeutic potentials
General control non-depressible 5 (GCN5) or lysine acetyltransferase 2A (KAT2A) is one of
the most highly studied histone acetyltransferases. It acts as both histone acetyltransferase …
the most highly studied histone acetyltransferases. It acts as both histone acetyltransferase …
Pathogenesis of ischemic stroke: role of epigenetic mechanisms
R Stanzione, M Cotugno, F Bianchi, S Marchitti, M Forte… - Genes, 2020 - mdpi.com
Epigenetics is the branch of molecular biology that studies modifications able to change
gene expression without altering the DNA sequence. Epigenetic modulations include DNA …
gene expression without altering the DNA sequence. Epigenetic modulations include DNA …
Epigenetic control of epithelial-to-mesenchymal transition and cancer metastasis
Y Wang, Y Shang - Experimental cell research, 2013 - Elsevier
Epithelial–mesenchymal transition (EMT) is vital for morphogenesis during embryonic
development and is also critical for the conversion of early stage tumors into invasive …
development and is also critical for the conversion of early stage tumors into invasive …
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine
C Pisano, G Pratesi, D Laccabue, F Zunino… - Clinical Cancer …, 2003 - AACR
Purpose: Antineoplastic drugs belonging to platinum or taxane families are severely
neurotoxic, inducing the onset of disabling peripheral neuropathies with different clinical …
neurotoxic, inducing the onset of disabling peripheral neuropathies with different clinical …
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo
JM Gajer, SD Furdas, A Gründer, M Gothwal… - Oncogenesis, 2015 - nature.com
We have previously described novel histone acetyltransferase (HAT) inhibitors that block
neuroblastoma cell growth in vitro. Here we show that two selected pyridoisothiazolone HAT …
neuroblastoma cell growth in vitro. Here we show that two selected pyridoisothiazolone HAT …