There is increasing effort in both the inpatient and outpatient setting to improve care,
function, and quality of life for children with congenital heart disease, and to decrease …

Congenital heart disease, particularly cyanotic congenital heart disease (CCHD), may lead
to a neurodevelopmental delay through central nervous system injury, more unstable central …

Background Infants undergoing cardiac surgery under cardiopulmonary bypass are
vulnerable to postoperative neurodevelopmental delays. Dexmedetomidine has been …

Neonates and infants surviving critical illness show impaired growth during critical illness
and are at risk for later neuropsychological impairments. Early identification of individuals …

Background Pediatric stroke, which is unique in that it represents a static insult to a
developing brain, often leads to long-term neurological disability. Neuroplasticity in infants …

Heart and brain development occur simultaneously during the embryogenesis, and both
organ development and injuries are interconnected. Early neuronal and cardiac injuries …

Background Adverse neurodevelopment is a common comorbidity associated with
congenital heart disease (CHD). The consequences of adverse neurodevelopment are seen …

Introduction: The objectives of this study were to assess the role of neuromarkers like glial
fibrillary acidic protein (GFAP), brain-derived neurotrophic factor (BDNF), protein S100 …

Rare pathogenic copy number variants (CNVs) are genetic rearrangements that have been
associated with an increased risk for congenital heart disorders (CHDs). However, the …

Cardiopulmonary bypass (CPB) provides cerebral oxygenation and blood flow (CBF) during
neonatal congenital heart surgery, but the impacts of CPB on brain oxygen supply and …