Recently, the comprehensive concept of “infection-related glomerulonephritis (IRGN)” has
replaced that of postinfectious glomerulonephritis (PIGN) because of the diverse infection …

Background: C3 glomerulopathy (C3G), a rare glomerular disease mediated by alternative
complement pathway dysregulation, is associated with a high rate of recurrence and graft …

Introduction Complement 3 glomerulopathy (C3G) is a rare kidney disease characterized by
dysregulation of the alternative pathway (AP) of the complement system. About 50% of …

Introduction Complement 3 glomerulopathy (C3G) is a rare inflammatory kidney disease
mediated by dysregulation of the alternative complement pathway. No targeted therapy …

Introduction Dysregulated complement activation is likely the primary driver of disease in C3
glomerulopathy (C3G) and contributes to other complement-mediated diseases, including …

Introduction The association between a change in proteinuria over time and its impact on
kidney prognosis has not been analysed in complement component 3 (C3) glomerulopathy …

Genetic testing has uncovered rare variants in complement proteins associated with
thrombotic microangiopathy (TMA) and C3 glomerulopathy (C3G). Approximately 50% are …

Heme oxygenase is a cytoprotective enzyme with strong antioxidant and anti-apoptotic
properties. Its cytoprotective role is mainly attributed to its enzymatic activity, which involves …

Background C3 glomerulopathy associated with monoclonal gammopathy (C3G-MIg) is a
rare entity. Herein we analysed the clinical and histologic features of a cohort of C3G-MIg …

Autoimmune kidney diseases occur due to the loss of tolerance to self-antigens, resulting in
inflammation and pathological damage to the kidneys. This review focuses on the known …