Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: current status and future direction

GJ Renukaradhya, XJ Meng, JG Calvert, M Roof… - Vaccine, 2015 - Elsevier
Within a few years of its emergence in the late 1980s, the PRRS virus had spread globally to
become the foremost infectious disease concern for the pork industry. Since 1994, modified …

[HTML][HTML] Porcine Macrophage Markers and Populations: An Update

B Álvarez, C Revilla, T Poderoso, A Ezquerra… - Cells, 2023 - mdpi.com
Besides its importance as a livestock species, pig is increasingly being used as an animal
model for biomedical research. Macrophages play critical roles in immunity to pathogens …

[HTML][HTML] Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in …

C Bernelin-Cottet, C Urien, J McCaffrey… - Journal of controlled …, 2019 - Elsevier
DNA vaccination is an attractive technology, based on its well-established manufacturing
process, safety profile, adaptability to rapidly combat pandemic pathogens, and stability at …

[HTML][HTML] Porcine reproductive and respiratory syndrome virus: immune escape and application of reverse genetics in attenuated live vaccine development

H Wang, Y Xu, W Feng - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely
prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from …

[HTML][HTML] Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine

EA Melgoza-González, L Bustamante-Córdova… - Frontiers in …, 2023 - frontiersin.org
Advances in antigen targeting in veterinary medicine have gained traction over the years as
an alternative approach for diseases that remain a challenge for traditional vaccines. In …

[HTML][HTML] Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+ CD8+ T, CD8+ T …

QM Cao, D Tian, CL Heffron, S Subramaniam… - Virology, 2019 - Elsevier
Immuno-stimulatory class I-restricted cytotoxic T lymphocytes (CTL) epitopes of porcine
reproductive and respiratory syndrome virus (PRRSV) are important for vaccine …

[HTML][HTML] Recombinant antibodies in veterinary medicine: An update

L Bustamante-Córdova… - Frontiers in Veterinary …, 2018 - frontiersin.org
The production of recombinant antibodies has had a tremendous impact on several
research fields, most prominently in biotechnology, immunology and medicine, enabling …

Infection Dynamics of Hepatitis E Virus in Wild-Type and Immunoglobulin Heavy Chain Knockout JH−/− Gnotobiotic Piglets

DM Yugo, CL Heffron, J Ryu, K Uh… - Journal of …, 2018 - Am Soc Microbiol
Hepatitis E virus (HEV), the causative agent of hepatitis E, is an important but incompletely
understood pathogen causing high mortality during pregnancy and leading to chronic …

Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs

S Subramaniam, D Cao, D Tian, QM Cao, C Overend… - Virus research, 2017 - Elsevier
Porcine epidemic diarrhea virus (PEDV) first emerged in the United States in 2013 causing
high mortality and morbidity in neonatal piglets with immense economic losses to the swine …

[HTML][HTML] A DNA prime immuno-potentiates a modified live vaccine against the porcine reproductive and respiratory syndrome virus but does not improve heterologous …

C Bernelin-Cottet, C Urien, M Fretaud, C Langevin… - Viruses, 2019 - mdpi.com
The porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus inducing
abortion in sows and respiratory disease in young pigs, is a leading infectious cause of …