DNA mismatch repair: functions and mechanisms

RR Iyer, A Pluciennik, V Burdett, PL Modrich - Chemical reviews, 2006 - ACS Publications
Mutations are rare events, occurring spontaneously at a frequency of 1 per 109-1010 base
pairs per cell division. 1, 2 Nucleotide misincorporation during DNA synthesis yields …

DNA mismatch repair: molecular mechanism, cancer, and ageing

P Hsieh, K Yamane - Mechanisms of ageing and development, 2008 - Elsevier
DNA mismatch repair (MMR) proteins are ubiquitous players in a diverse array of important
cellular functions. In its role in post-replication repair, MMR safeguards the genome …

DNA mismatch repair in eukaryotes and bacteria

K Fukui - Journal of nucleic acids, 2010 - Wiley Online Library
DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA
replication errors. The fundamental mechanisms and proteins involved in the early reactions …

[HTML][HTML] The conserved molecular machinery in DNA mismatch repair enzyme structures

FS Groothuizen, TK Sixma - DNA repair, 2016 - Elsevier
The machinery of DNA mismatch repair enzymes is highly conserved in evolution. The
process is initiated by recognition of a DNA mismatch, and validated by ATP and the …

Mismatch repair and homeologous recombination

KC Tham, R Kanaar, JHG Lebbink - DNA repair, 2016 - Elsevier
DNA mismatch repair influences the outcome of recombination events between diverging
DNA sequences. Here we discuss how mismatch repair proteins are active in different …

Conditional gene silencing of multiple genes with antisense RNAs and generation of a mutator strain of Escherichia coli

N Nakashima, T Tamura - Nucleic acids research, 2009 - academic.oup.com
In this study, we describe a method of simultaneous conditional gene silencing of up to four
genes in Escherichia coli by using antisense RNAs. We used antisense RNAs with paired …

The impact of sequence divergence and DNA mismatch repair on homeologous recombination in Arabidopsis

L Li, M Jean, F Belzile - The Plant Journal, 2006 - Wiley Online Library
We examined the effects of substrate divergence and DNA mismatch repair (MMR) on
recombination in Arabidopsis thaliana. Relative to the frequency observed in plants with a …

Genome editing outcomes reveal mycobacterial NucS participates in a short-patch repair of DNA mismatches

T Islam, EA Josephs - Nucleic Acids Research, 2024 - academic.oup.com
In the canonical DNA mismatch repair (MMR) mechanism in bacteria, if a nucleotide is
incorrectly mis-paired with the template strand during replication, the resulting repair of this …

DNA mismatch repair

MG Marinus - EcoSal Plus, 2012 - Am Soc Microbiol
DNA mismatch repair (MMR) corrects replication errors in newly synthesized DNA. It also
has an antirecombination action on heteroduplexes that contain similar but not identical …

MSH2 is essential for the preservation of genome integrity and prevents homeologous recombination in the moss Physcomitrella patens

B Trouiller, DG Schaefer, F Charlot… - Nucleic acids …, 2006 - academic.oup.com
MSH2 is a central component of the mismatch repair pathway that targets mismatches
arising during DNA replication, homologous recombination (HR) and in response to …