Atomic force microscopy (AFM), which provides true 3D surface topography, can also be
used to determine the geometric parameters of proteins quantitatively at a single molecular …

DNA mismatch repair (MMR) in mammalian cells or Escherichia coli dam mutants increases
the cytotoxic effects of cisplatin and N-methyl-N′-nitro-N-nitrosoguanidine (MNNG). We …

We developed a sensitive, homogeneous fluorescence assay for the detection of DNA
mismatches and DNA damage based on the mismatch repair (MMR) protein MutS. The …

Meiosis is a conserved eukaryotic cell division that increases genetic diversity in progeny.
During meiosis, homologous chromosomes pair and undergo reciprocal exchange, called …

Bacteria have evolved to survive periods of harsh conditions and to grow and divide rapidly
under periods of rich conditions. The shortest sustainable doubling times observed for …

Gene silencing using antisense RNA or RNA interference (RNAi) is now a popular method
used in eukaryotes. However, RNAi mechanism is absent in bacteria, and hence, single …

В обзоре приведены общие представления о репарации неканонических пар
нуклеотидов («мисматчей») в ДНК (MMR). На сегодняшний день определены основные …

Ein wichtiger Schritt im mismatch Reparatur System (MMR) ist die Ausbildung des ternären
Komplexes aus MutS, MutL und DNA nach der Erkennung der Fehlpaarung durch MutS …

Für die Untersuchung/Unterscheidung der verschiedenen Modelle der DNA-mismatch-
Reparatur sind geeignete, qualitativ hochwertige DNA-Substrate entscheidend. Die …

Mispaired bases in DNA are recognized by the DNA mismatch repair protein MutS, which
then signals for repair of the error. During mismatch recognition, dimers of MutS embrace the …