[HTML][HTML] Role of serotonin receptor signaling in cancer cells and anti-tumor immunity
S Karmakar, G Lal - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …
Serotonin in the gut: Blessing or a curse
S Banskota, JE Ghia, WI Khan - Biochimie, 2019 - Elsevier
Abstract Serotonin (5-hydroxytryptamine or 5-HT) once most extensively studied as a
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor
M León-Ponte, GP Ahern, PJ O'Connell - Blood, 2007 - ashpublications.org
Although typically considered a neurotransmitter, there is substantial evidence that serotonin
(5-HT) plays an important role in the pathogenesis of inflammatory disorders. Despite these …
(5-HT) plays an important role in the pathogenesis of inflammatory disorders. Despite these …
Serotonin and cancer: what is the link?
D Sarrouilhe, J Clarhaut, N Defamie… - Current molecular …, 2015 - ingentaconnect.com
Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine that acts as a
neurotransmitter in the central nervous system, local mediator in the gut and vasoactive …
neurotransmitter in the central nervous system, local mediator in the gut and vasoactive …
Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
VP Pai, AM Marshall, LL Hernandez, AR Buckley… - Breast cancer …, 2009 - Springer
Introduction The breast microenvironment can either retard or accelerate the events
associated with progression of latent cancers. However, the actions of local physiological …
associated with progression of latent cancers. However, the actions of local physiological …
Human mast cells are capable of serotonin synthesis and release
NM Kushnir-Sukhov, JM Brown, Y Wu… - Journal of Allergy and …, 2007 - jacionline.org
The cell-associated serotonin content of human mast cells was 8.6 to 14.4 ng/106 cells;
supernatant serotonin content was 1.8 to 2.8 ng/106 cells. Media used for human mast cell …
supernatant serotonin content was 1.8 to 2.8 ng/106 cells. Media used for human mast cell …
Serotonin activates glycolysis and mitochondria biogenesis in human breast cancer cells through activation of the Jak1/STAT3/ERK1/2 and adenylate cyclase/PKA …
M Sola-Penna, LP Paixão, JR Branco… - British journal of …, 2020 - nature.com
Background Although produced by several types of tumours, the role of serotonin on cancer
biology is yet to be understood. Methods The effects of serotonin (5-HT) on human breast …
biology is yet to be understood. Methods The effects of serotonin (5-HT) on human breast …
Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways
C Li, J Han, Q Yao, C Zou, Y Xu, C Zhang… - Nucleic acids …, 2013 - academic.oup.com
Various 'omics' technologies, including microarrays and gas chromatography mass
spectrometry, can be used to identify hundreds of interesting genes, proteins and …
spectrometry, can be used to identify hundreds of interesting genes, proteins and …
Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin …
Background Triple-negative breast cancer (TNBC) has a high risk of relapse and there are
few chemotherapy options. Although 5-hydroxytryptamine (5-HT, serotonin) signaling …
few chemotherapy options. Although 5-hydroxytryptamine (5-HT, serotonin) signaling …
Monoamines in glioblastoma: complex biology with therapeutic potential
SP Caragher, RR Hall, R Ahsan, AU Ahmed - Neuro-oncology, 2018 - academic.oup.com
Glioblastoma (GBM) is characterized by extremely poor prognoses, despite the use of gross
surgical resection, alkylating chemotherapeutic agents, and radiotherapy. Evidence …
surgical resection, alkylating chemotherapeutic agents, and radiotherapy. Evidence …