The survival rate for metastatic osteosarcoma has not improved for several decades, since
the introduction and refinement of chemotherapy as a treatment in addition to surgery. Over …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcoma is a rare malignancy arising from mesenchymal tissue, and represents the
most common bone sarcoma. The management of osteosarcoma is challenging, and …

TIMM13 (translocase of inner mitochondrial membrane 13) located at the mitochondrial
intermembrane space is vital for the integrity and function of mitochondria. We found that the …

Background Osteosarcoma is the most common bone cancer, mainly occurring in children
and adolescents, among which distant metastasis (DM) still leads to a poor prognosis …

Osteosarcoma (OS) is a highly aggressive form of bone cancer that predominantly affects
adolescents and young adults. In this study, we have undertaken an investigation into the …

Background: There is no standard posttreatment for patients with advanced hepatocellular
carcinoma (HCC) in whom lenvatinib therapy has failed. This study aimed to investigate …

Bone sarcomas are a heterogeneous group of rare tumors with a predominance in the
young population. Few options of systemic treatment are available once they become …

Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties, a
high incidence of pulmonary metastasis and a poor prognosis. Chemotherapy is the …

Osteosarcoma (OS) is an aggressive primary bone malignancy that metastasizes rapidly.
The standard of care has changed little over the previous four decades, and survival rates …