[HTML][HTML] Potential uses of olive oil secoiridoids for the prevention and treatment of cancer: a narrative review of preclinical studies
MR Emma, G Augello, V Di Stefano, A Azzolina… - International journal of …, 2021 - mdpi.com
The Mediterranean diet (MD) is a combination of foods mainly rich in antioxidants and anti-
inflammatory nutrients that have been shown to have many health-enhancing effects. Extra …
inflammatory nutrients that have been shown to have many health-enhancing effects. Extra …
[HTML][HTML] Targets involved in the anti-cancer activity of quercetin in breast, colorectal and liver neoplasms
Phytochemicals have long been effective partners in the fight against several diseases,
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …
[HTML][HTML] Oleacein attenuates lipopolysaccharide-induced inflammation in THP-1-derived macrophages by the inhibition of TLR4/MyD88/NF-κB pathway
It is known that plant phenolic compounds exert anti-inflammatory activity through both anti-
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …
Pressurized liquid extraction optimization from supercritical defatted olive pomace: a green and selective phenolic extraction process
N Katsinas, A Bento da Silva… - ACS Sustainable …, 2021 - ACS Publications
Olive pomace (OP) is the main by-product of the olive oil industry produced in large
quantities. Its valorization as a source of phenolic bioactive compounds is paramount for the …
quantities. Its valorization as a source of phenolic bioactive compounds is paramount for the …
An updated review on the potential antineoplastic actions of oleuropein
Y Zheng, Z Liu, X Yang, L Liu… - Phytotherapy Research, 2022 - Wiley Online Library
Oleuropein is an ester of elenolic acid and hydroxytyrosol (3, 4‐dihydroxyphenylethanol). It
is a phenolic compound and the most luxuriant in olives. The detailed information related to …
is a phenolic compound and the most luxuriant in olives. The detailed information related to …
[HTML][HTML] miRNA modulation and antitumor activity by the extra-virgin olive oil polyphenol oleacein in human melanoma cells
Extra-virgin olive oil (EVOO) polyphenols contribute to Mediterranean diet health-promoting
properties. One of the most abundant secoiridoid present in EVOO, Oleacein (OA) …
properties. One of the most abundant secoiridoid present in EVOO, Oleacein (OA) …
[HTML][HTML] Effects of oleacein, a new epinutraceutical bioproduct from extra virgin olive oil, in LPS-activated murine immune cells
R Muñoz-García, M Sánchez-Hidalgo, T Montoya… - Pharmaceuticals, 2022 - mdpi.com
The present study was designed to evaluate the immunomodulatory effects of the
secoiridoid from extra virgin olive oil, oleacein (OLA), deepening into the possible signaling …
secoiridoid from extra virgin olive oil, oleacein (OLA), deepening into the possible signaling …
[HTML][HTML] New affordable methods for large-scale isolation of major olive secoiridoids and systematic comparative study of their antiproliferative/cytotoxic effect on …
A Papakonstantinou, P Koumarianou… - International Journal of …, 2022 - mdpi.com
Olive oil phenols (OOPs) are associated with the prevention of many human cancers. Some
of these have been shown to inhibit cell proliferation and induce apoptosis. However, no …
of these have been shown to inhibit cell proliferation and induce apoptosis. However, no …
[HTML][HTML] Oleuropein counteracts both the proliferation and migration of intra-and extragonadal seminoma cells
S Bossio, A Perri, R Malivindi, F Giordano, V Rago… - Nutrients, 2022 - mdpi.com
Recent and growing literature has reported that oleuropein (OLE), the main polyphenol in
olive leaf extract, inhibits tumor cell proliferation and reduces the invasiveness properties of …
olive leaf extract, inhibits tumor cell proliferation and reduces the invasiveness properties of …
[HTML][HTML] The SIRT2 pathway is involved in the antiproliferative effect of flavanones in human leukemia monocytic THP-1 cells
Acute myeloid leukemia (AML) represents the most alarming hematological disease for
adults. Several genetic modifications are known to be pivotal in AML; however, SIRT2 over …
adults. Several genetic modifications are known to be pivotal in AML; however, SIRT2 over …