The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation
CN Kotton, N Kamar, D Wojciechowski, M Eder… - …, 2024 - journals.lww.com
BK polyomavirus (BKPyV) remains a significant challenge after kidney transplantation.
International experts reviewed current evidence and updated recommendations according …
International experts reviewed current evidence and updated recommendations according …
BK polyomavirus—biology, genomic variation and diagnosis
J Furmaga, M Kowalczyk, T Zapolski, O Furmaga… - Viruses, 2021 - mdpi.com
The BK polyomavirus (BKPyV), a representative of the family Polyomaviridae, is widespread
in the human population. While the virus does not cause significant clinical symptoms in …
in the human population. While the virus does not cause significant clinical symptoms in …
Time-dependent variations in BK polyomavirus genome from kidney transplant recipients with persistent viremia
O Mineeva-Sangwo, E Van Loon, G Andrei… - Scientific Reports, 2023 - nature.com
BK polyomavirus (BKPyV) is a human DNA virus that resides latent in the host's renal tissue.
Reactivation occurs occasionally and in case of kidney transplantation, it can lead to …
Reactivation occurs occasionally and in case of kidney transplantation, it can lead to …
[HTML][HTML] Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus
MN Sorin, A Di Maio, LM Silva, D Ebert, CP Delannoy… - Cell Reports, 2023 - cell.com
BK polyomavirus (BKPyV) is an opportunistic pathogen that uses the b-series gangliosides
GD1b and GT1b as entry receptors. Here, we characterize the impact of naturally occurring …
GD1b and GT1b as entry receptors. Here, we characterize the impact of naturally occurring …
[HTML][HTML] A multivalent polyomavirus vaccine elicits durable neutralizing antibody responses in macaques
A Peretti, DG Scorpio, WP Kong, YYS Pang… - Vaccine, 2023 - Elsevier
Abstract In 2019, there were about 100,000 kidney transplants globally, with more than a
quarter of them performed in the United States. Unfortunately, some engrafted organs are …
quarter of them performed in the United States. Unfortunately, some engrafted organs are …
Structural analysis of merkel cell polyomavirus (MCPyV) viral capsid protein 1 (VP1) in HIV-1 infected individuals
C Prezioso, M Bianchi, F Obregon, M Ciotti… - International Journal of …, 2020 - mdpi.com
Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates
virus attachment to host cell receptors and is the major immune target. Given the limited data …
virus attachment to host cell receptors and is the major immune target. Given the limited data …
Quantification of APOBEC3 Mutation Rates Affecting the VP1 Gene of BK Polyomavirus In Vivo
D McIlroy, C Peltier, ML Nguyen, L Manceau… - Viruses, 2022 - mdpi.com
Mutations in the BK polyomavirus (BKPyV) capsid accumulate in kidney transplant (KTx)
recipients with persistent virus replication. They are associated with neutralization escape …
recipients with persistent virus replication. They are associated with neutralization escape …
JCPyV VP1 mutations in progressive multifocal leukoencephalopathy: altering tropism or mediating immune evasion?
MD Lauver, AE Lukacher - Viruses, 2020 - mdpi.com
Polyomaviruses are ubiquitous human pathogens that cause lifelong, asymptomatic
infections in healthy individuals. Although these viruses are restrained by an intact immune …
infections in healthy individuals. Although these viruses are restrained by an intact immune …
Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study
J Durairaj, OM Follonier, K Leuzinger, LT Alexander… - Msphere, 2024 - Am Soc Microbiol
ABSTRACT BK polyomavirus (BKPyV) is a double-stranded DNA virus causing
nephropathy, hemorrhagic cystitis, and urothelial cancer in transplant patients. The BKPyV …
nephropathy, hemorrhagic cystitis, and urothelial cancer in transplant patients. The BKPyV …
Challenges and opportunities in research on BK virus infection after renal transplantation
Y Tang, Z Wang, D Du - International Immunopharmacology, 2024 - Elsevier
Renal transplantation is one of the primary approaches for curing end-stage kidney disease.
With advancements in immunosuppressive agents, the short-term and long-term survival …
With advancements in immunosuppressive agents, the short-term and long-term survival …