Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies

T Tanaka, Y Nakajima-Takagi, K Aoyama… - Journal of Experimental …, 2017 - rupress.org
Recurrent inactivating mutations have been identified in various hematological
malignancies in the X-linked BCOR gene encoding BCL6 corepressor (BCOR); however, its …

BCOR-CCNB3 undifferentiated sarcoma—does immunohistochemistry help in the identification?

K Ludwig, R Alaggio, A Zin, M Peron… - Pediatric and …, 2017 - journals.sagepub.com
Recent methodology has enabled the identification of some new genetic subgroups within
the melting pot of lesions presently classified by the 2013 WHO classification as …

AP2a enhanced the osteogenic differentiation of mesenchymal stem cells by inhibiting the formation of YAP/RUNX2 complex and BARX1 transcription

X Lin, H Yang, L Wang, W Li, S Diao, J Du… - Cell …, 2019 - Wiley Online Library
Objectives Bone regeneration by bone tissue engineering is a therapeutic option for bone
defects. Improving the osteogenic differentiation of mesenchymal stem cells (MSCs) is …

Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1

R Gao, R Dong, J Du, P Ma, S Wang, Z Fan - Molecular and cellular …, 2013 - Springer
Mesenchymal stem cells (MSCs) are a reliable resource for tissue regeneration; although,
the molecular mechanisms of their differentiation and proliferation are not clearly …

[HTML][HTML] Molecular signature of biological aggressiveness in clear cell sarcoma of the kidney (CCSK)

M Fiore, A Taddia, V Indio, SN Bertuccio… - International Journal of …, 2023 - mdpi.com
Clear cell sarcoma of the kidney (CCSK) is a rare pediatric renal tumor with a worse
prognosis than Wilms' tumor. Although recently, BCOR internal tandem duplication (ITD) has …

Sjögren's syndrome X‐chromosome dose effect: An epigenetic perspective

JLC Mougeot, BD Noll, FK Bahrani Mougeot - Oral diseases, 2019 - Wiley Online Library
Sjögren's syndrome (SS) is a chronic autoimmune disease affecting exocrine glands leading
to mouth and eyes dryness. The extent to which epigenetic DNA methylation changes are …

[HTML][HTML] Epigenetic regulation of adipogenic differentiation by histone lysine demethylation

GI Nic-Can, BA Rodas-Junco… - International Journal of …, 2019 - mdpi.com
Obesity is a rising public health problem that contributes to the development of several
metabolic diseases and cancer. Adipocyte precursors outside of adipose depots that expand …

Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage

RM Green, W Feng, T Phang, JL Fish… - Disease models & …, 2015 - journals.biologists.com
Failure of facial prominence fusion causes cleft lip and palate (CL/P), a common human birth
defect. Several potential mechanisms can be envisioned that would result in CL/P, including …

[HTML][HTML] SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

L Jin, Y Cao, G Yu, J Wang, X Lin, L Ge, J Du… - Cellular & molecular …, 2017 - Springer
Background Exploring the molecular mechanisms underlying directed differentiation is
helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our …

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics

FKF Kommoss, D Stichel, D Schrimpf… - Journal of cancer …, 2020 - Springer
Purpose Uterine neoplasms comprise a broad spectrum of lesions, some of which may pose
a diagnostic challenge even to experienced pathologists. Recently, genome-wide DNA …