[HTML][HTML] Biomarkers in neurodegenerative diseases: proteomics spotlight on ALS and Parkinson's disease

R Raghunathan, K Turajane, LC Wong - International Journal of …, 2022 - mdpi.com
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …

[PDF][PDF] Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition

OJ Ziff, J Harley, Y Wang, J Neeves, G Tyzack… - Neuron, 2023 - cell.com
Amyotrophic lateral sclerosis (ALS) is characterized by nucleocytoplasmic mislocalization of
the RNA-binding protein (RBP) TDP-43. However, emerging evidence suggests more …

Fall risk, sleep behavior, and sleep-related movement disorders in Young urbanites exposed to air pollution

L Calderón-Garcidueñas, R Kulesza… - Journal of …, 2023 - content.iospress.com
Background: Quadruple aberrant hyperphosphorylated tau, amyloid-ß, α-synuclein, and
TDP-43 pathology had been documented in 202/203 forensic autopsies in Metropolitan …

[HTML][HTML] Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?

B Proaño, J Casani-Cubel, M Benlloch… - Biomedicines, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized by
the loss of upper and lower motor neurons (MNs) in the cerebral cortex, brainstem and …

FUS-P525L juvenile amyotrophic lateral sclerosis and intellectual disability: Evidence for association and oligogenic inheritance

O Goldstein, T Inbar, M Kedmi, M Gana-Weisz… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Amyotrophic lateral sclerosis (ALS) is characterized by upper
and lower motor neuron degeneration, with juvenile ALS (jALS) defined as disease with age …

[PDF][PDF] Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis? Biomedicines 2022, 10, 2084

B Proaño, J Casani-Cubel, M Benlloch… - 2022 - researchgate.net
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is characterized by
the loss of upper and lower motor neurons (MNs) in the cerebral cortex, brainstem and …

[PDF][PDF] ALS associated mutations in ANXA11 cause distal axonopathy, disrupt calcium signalling, and influence RNA dynamics in patient derived motor neurons

E Hedges - 2023 - kclpure.kcl.ac.uk
The neurodegenerative disease amyotrophic lateral sclerosis (ALS) is characteristically
heterogeneous in both genetic causality and cellular pathology. In ALS, the upper and lower …