A variety of mechanisms have been suggested as the means by which infections can initiate
and/or exacerbate autoimmune diseases. One mechanism is molecular mimicry, where a …

Virus infections and autoimmune disease have long been linked. These infections often
precede the occurrence of inflammation in the target organ. Several mechanisms often used …

Immune memory responses to previously encountered pathogens can sometimes alter the
immune response to and the course of infection of an unrelated pathogen by a process …

Granulomatous meningoencephalomyelitis, necrotizing meningoencephalitis, and
necrotizing leukoencephalitis are common inflammatory conditions of the canine central …

Microorganisms induce strong immune responses, most of which are specific for their
encoded antigens. However, microbial infections can also trigger responses against self …

Group B coxsackieviruses (CVB) are believed to trigger some cases of human type 1
diabetes (T1D), although the mechanism by which this may occur has not been shown. We …

Polymicrobial infections have been associated with plausible immune mediated diseases,
including multiple sclerosis (MS). Virus infection can prime autoimmune T cells specific for …

One of the most common demyelinating central nervous system (CNS) diseases in humans
is multiple sclerosis (MS). The disease can be very debilitating with vision loss, motor and …

Autoimmune reactions associated with MS involve genetic and environmental factors.
Because murine coronaviruses induce an MS-like disease, the human coronaviruses …

Substantial research has been directed towards the development of a new generation of
vaccines that are based on the inclusion of immunogenic epitopes in recombinant vectors …