[HTML][HTML] Biological activity of selenium and its impact on human health

G Genchi, G Lauria, A Catalano, MS Sinicropi… - International journal of …, 2023 - mdpi.com
Selenium (Se) is a naturally occurring metalloid element essential to human and animal
health in trace amounts but it is harmful in excess. Se plays a substantial role in the …

[HTML][HTML] Noncoding RNAs in gastric cancer: implications for drug resistance

L Wei, J Sun, N Zhang, Y Zheng, X Wang, L Lv, J Liu… - Molecular cancer, 2020 - Springer
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-
related deaths worldwide. Advanced gastric cancer patients can notably benefit from …

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

[HTML][HTML] A summary of new findings on the biological effects of selenium in selected animal species—a critical review

B Hosnedlova, M Kepinska, S Skalickova… - International journal of …, 2017 - mdpi.com
Selenium is an essential trace element important for many physiological processes,
especially for the functions of immune and reproductive systems, metabolism of thyroid …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

[HTML][HTML] The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression

W Wu, T Yu, Y Wu, W Tian, J Zhang, Y Wang - Journal of Experimental & …, 2019 - Springer
Background Glioblastoma multiforme (GBM) is the most common and aggressive form of
astrocytoma among adult brain tumors. Multiple studies have shown that long non-coding …

Mechanisms of resistance to chemotherapy in gastric cancer

JJG Marin, R Al-Abdulla, E Lozano… - Anti-Cancer Agents …, 2016 - ingentaconnect.com
Although surgical resection is the standard curative therapy for gastric cancer, these tumors
are often diagnosed at an advanced stage, when surgery is not recommended. Alternative …

[HTML][HTML] Mechanisms of action and clinical implications of MicroRNAs in the drug resistance of gastric cancer

Y Liu, X Ao, G Ji, Y Zhang, W Yu, J Wang - Frontiers in oncology, 2021 - frontiersin.org
Gastric cancer (GC) is one of the most common malignant tumors of digestive systems
worldwide, with high recurrence and mortality. Chemotherapy is still the standard treatment …

Epigenetic effects of selenium and their implications for health

B Speckmann, T Grune - Epigenetics, 2015 - Taylor & Francis
Alterations of epigenetic marks are linked to normal development and cellular differentiation
as well as to the progression of common chronic diseases. The plasticity of these marks …

[HTML][HTML] MicroRNA-421 regulated by HIF-1α promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric …

X Ge, X Liu, F Lin, P Li, K Liu, R Geng, C Dai, Y Lin… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Hypoxia and dysregulation of microRNAs (miRNAs) have been identified as crucial factors
in carcinogenesis. However, the potential mechanisms of HIF-1α and miR-421 in gastric …