Venous thrombosis (VT), a leading cause of morbidity and mortality worldwide, has recently
been linked to neutrophil activation and release of neutrophil extracellular traps (NETs) via a …

Clinical observations and accumulating laboratory evidence support a complex interplay
between coagulation, inflammation, innate immunity and fibrinolysis in venous …

Deep vein thrombosis and pulmonary embolism are a significant health care concern,
representing a major source of mortality and morbidity. In order to understand the …

Observational studies have shown that inflammatory cells accumulate within the thrombus
and surrounding vein wall during the natural history of venous thrombosis. More recent …

Cerebral venous thrombosis (CVT) is a rare form of cerebrovascular disease that impairs
people's wellbeing and quality of life. Inflammation is considered to play an important role in …

Murine models are widely used valuable tools to study deep vein thrombosis. Leading
experts in venous thrombosis research came together through the American Venous Forum …

Clotting and inflammation are effective danger response patterns positively selected by
evolution to limit fatal bleeding and pathogen invasion upon traumatic injuries. As a trade …

Venous thromboembolism (VTE) is a pathology encompassing deep vein thrombosis (DVT)
and pulmonary embolism (PE) associated with high morbidity and mortality. Because …

Notch signaling is a major pathway in cell fate decisions. Since the first reports showing the
major role of Notch in embryonic development, a considerable and still growing literature …

Toll-like receptors (TLRs), a class of pattern recognition proteins, play an integral role in the
modulation of systemic inflammatory responses. Cerebrovascular diseases (CVDs) are a …