Insulin-like growth factors-I and-II differentially regulate endogenous acetylcholine release from the rat hippocampal formation
S Kar, D Seto, S Dore, UK Hanisch… - Proceedings of the …, 1997 - National Acad Sciences
Insulin-like growth factors-I and-II (IGF-I and-II) are structurally related mitogenic
polypeptides with potent growth promoting effects. These peptides and their corresponding …
polypeptides with potent growth promoting effects. These peptides and their corresponding …
Update on PET tracer development for muscarinic acetylcholine receptors
The muscarinic cholinergic system regulates peripheral and central nervous system
functions, and, thus, their potential as a therapeutic target for several neurodegenerative …
functions, and, thus, their potential as a therapeutic target for several neurodegenerative …
[图书][B] Parkinson's disease
RF Pfeiffer, ZK Wszolek, M Ebadi - 2004 - taylorfrancis.com
Recent research is leading to an ever-increasing range of investigative approaches whose
aim is to achieve effective neuroprotective or neurorestorative treatment for individuals …
aim is to achieve effective neuroprotective or neurorestorative treatment for individuals …
Rivastigmine for refractory REM behavior disorder in mild cognitive impairment
V Brunetti, A Losurdo, E Testani… - Current Alzheimer …, 2014 - ingentaconnect.com
Background: Mild Cognitive Impairment (MCI) and REM Behavior Disorder (RBD) are both
associated with a degeneration of ponto-medullary cholinergic pathways. Methods: We …
associated with a degeneration of ponto-medullary cholinergic pathways. Methods: We …
Plasma thiamine deficiency associated with Alzheimer's disease but not Parkinson's disease
M Gold, RA Hauser, MF Chen - Metabolic brain disease, 1998 - Springer
In this study we compared plasma and erythrocyte thiamine levels in a group of patients with
idiopathic Parkinson's Disease (iPD) to a group of patients with probable Alzheimer's …
idiopathic Parkinson's Disease (iPD) to a group of patients with probable Alzheimer's …
G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases
M Guerram, LY Zhang, ZZ Jiang - Neurochemistry international, 2016 - Elsevier
Neurodegenerative and cerebrovascular diseases are frequent in elderly populations and
comprise primarily of dementia (mainly Alzheimer's disease) Parkinson's disease and …
comprise primarily of dementia (mainly Alzheimer's disease) Parkinson's disease and …
Basal forebrain cholinergic systems as circuits through which traumatic stress disrupts emotional memory regulation
Contextual and spatial systems facilitate changes in emotional memory regulation brought
on by traumatic stress. Cholinergic basal forebrain (chBF) neurons provide input to …
on by traumatic stress. Cholinergic basal forebrain (chBF) neurons provide input to …
Insulin‐like growth factor‐I and its receptor in the frontal cortex, hippocampus, and cerebellum of normal human and Alzheimer disease brains
S Jafferali, Y Dumont, F Sotty, Y Robitaille, R Quirion… - Synapse, 2000 - Wiley Online Library
Assimilated evidence indicates that the neurotoxic potential of amyloid β (Aβ) peptide and
an alteration in the level of growth factor (s) may possibly be involved in the loss of neurons …
an alteration in the level of growth factor (s) may possibly be involved in the loss of neurons …
Choline reverses scopolamine-induced memory impairment by improving memory reconsolidation
It is widely known that pre-training systemic administration of the muscarinic antagonist
scopolamine (SCP)(0.5 mg/kg, ip) leads to anterograde memory impairment in retention …
scopolamine (SCP)(0.5 mg/kg, ip) leads to anterograde memory impairment in retention …