[HTML][HTML] Molecular mechanisms of radiation-induced cancer cell death: a primer

J Sia, R Szmyd, E Hau, HE Gee - Frontiers in cell and developmental …, 2020 - frontiersin.org
Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment
resistance remains a clinical problem. There have been recent advances in understanding …

Cancer radiosensitizers

H Wang, X Mu, H He, XD Zhang - Trends in pharmacological sciences, 2018 - cell.com
Radiotherapy (RT) is a mainstay treatment for many types of cancer, although it is still a
large challenge to enhance radiation damage to tumor tissue and reduce side effects to …

[HTML][HTML] The linear quadratic model: usage, interpretation and challenges

SJ McMahon - Physics in Medicine & Biology, 2018 - iopscience.iop.org
The linear-quadratic model is one of the key tools in radiation biology and physics. It
provides a simple relationship between cell survival and delivered dose:, and has been …

[HTML][HTML] Recent developments in radiotherapy

DE Citrin - New England journal of medicine, 2017 - Mass Medical Soc
Recent Developments in Radiotherapy | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Report of the AAPM TG‐256 on the relative biological effectiveness of proton beams in radiation therapy

H Paganetti, E Blakely, A Carabe‐Fernandez… - Medical …, 2019 - Wiley Online Library
The biological effectiveness of proton beams relative to photon beams in radiation therapy
has been taken to be 1.1 throughout the history of proton therapy. While potentially …

ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy

G Sgouros, WE Bolch, A Chiti… - Journal of the …, 2021 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Targeting hypoxia to improve non–small cell lung cancer outcome

A Salem, MC Asselin, B Reymen… - JNCI: Journal of the …, 2018 - academic.oup.com
Oxygen deprivation (hypoxia) in non–small cell lung cancer (NSCLC) is an important factor
in treatment resistance and poor survival. Hypoxia is an attractive therapeutic target …

[HTML][HTML] Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: a systematic review

SGC Kroeze, C Fritz, M Hoyer, SS Lo, U Ricardi… - Cancer treatment …, 2017 - Elsevier
Background and purpose Both stereotactic radiotherapy (SRT) and immune-or targeted
therapy play an increasingly important role in personalized treatment of metastatic disease …

[HTML][HTML] Repeated stereotactic body radiotherapy for oligometastatic prostate cancer recurrence

K Decaestecker, G De Meerleer, B Lambert, L Delrue… - Radiation …, 2014 - Springer
Purpose To assess the outcome of prostate cancer (PCa) patients diagnosed with
oligometastatic disease at recurrence and treated with stereotactic body radiotherapy …

[HTML][HTML] Applications of radiomics and machine learning for radiotherapy of malignant brain tumors

M Kocher, MI Ruge, N Galldiks, P Lohmann - Strahlentherapie und …, 2020 - Springer
Background Magnetic resonance imaging (MRI) and amino acid positron-emission
tomography (PET) of the brain contain a vast amount of structural and functional information …