Noncoding microRNAs are powerful epigenetic regulators of cellular processes by their
ability to target and suppress expression of numerous protein-coding mRNAs. This …

Treating bone infections and ensuring bone repair is one of the greatest global challenges
of modern orthopedics, made complex by antimicrobial resistance (AMR) risks due to long …

Osteoporosis (OP) is a prevalent age-related disease that is characterized by a decrease in
bone mineral density (BMD) and systemic bone microarchitectural disorders. With age …

Pineal melatonin and the cortisol awakening response (CAR) are integral aspects of the
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …

The pathogenesis of intervertebral disc degeneration (IVDD) is attributed to metabolic
dysregulation within the extracellular matrix and heightened apoptosis of nucleus pulposus …

Aging can lead to various disorders in organisms and with the escalating impact of
population aging, the incidence of age-related diseases is steadily increasing. As a major …

MicroRNAs (miRNAs) are short RNA molecules that are not involved in coding for proteins.
They have a significant function in regulating gene expression after the process of …

Aim The premixed bioceramic sealer iRoot SP that is widely used clinically has been
reported to kill bacterial biofilms and promote osteogenic differentiation of human stem cells …

Background Osteoporosis, among other bone diseases, has become a prevalent cause of
decreased quality of life in older and postmenopausal women. Traditional anti-osteoporotic …

Magnesium-based composites are a focal point in biomaterials research. However, the rapid
degradation rate of magnesium alloys does not align with the healing time of bone tissue …