Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors

G Pethő, PW Reeh - Physiological reviews, 2012 - journals.physiology.org
Peripheral mediators can contribute to the development and maintenance of inflammatory
and neuropathic pain and its concomitants (hyperalgesia and allodynia) via two …

Pain in rheumatoid arthritis: models and mechanisms

DB Bas, J Su, G Wigerblad, CI Svensson - Pain management, 2016 - Taylor & Francis
Pain is one of the most challenging symptoms for patients with rheumatoid arthritis (RA). RA-
related pain is frequently considered to be solely a consequence of inflammation in the …

Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response

FC Fachini-Queiroz, R Kummer… - Evidence‐Based …, 2012 - Wiley Online Library
Thyme (Thymus vulgaris L., Lamiaceae) is an aromatic and medicinal plant that has been
used in folk medicine, phytopharmaceutical preparations, food preservatives, and as an …

Structural characterization and anti-inflammatory activity of a polysaccharide from the lignified okra

Y Liu, Y Ye, X Hu, J Wang - Carbohydrate Polymers, 2021 - Elsevier
Abstract The polysaccharide (AP1-b) of molecular weight 6.59× 10 5 Da was isolated from
lignified okra (Abelmoschus esculentus (L.) Moench) by hot-water extraction, 40% ethanol …

Anti‐Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo

JC Liao, JS Deng, CS Chiu, WC Hou… - Evidence‐Based …, 2012 - Wiley Online Library
We have investigated the anti‐inflammatory effects of Cinnamomum cassia constituents
(cinnamic aldehyde, cinnamic alcohol, cinnamic acid, and coumarin) using …

Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord

P Honore, NM Luger, MAC Sabino, MJ Schwei… - Nature medicine, 2000 - nature.com
Bone cancer pain is common among cancer patients and can have a devastating effect on
their quality of life. A chief problem in designing new therapies for bone cancer pain is that it …

[HTML][HTML] The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation

JJ Inglis, A Nissim, DM Lees, SP Hunt… - Arthritis research & …, 2005 - Springer
Therapies directed against tumour necrosis factor (TNF) are effective for the treatment of
rheumatoid arthritis and reduce pain scores in this condition. In this study, we sought to …

Analgesic and antiinflammatory activities of the aqueous extract from Plectranthus amboinicus (Lour.) Spreng. both in vitro and in vivo

YJ Chiu, TH Huang, CS Chiu, TC Lu… - Evidence‐Based …, 2012 - Wiley Online Library
Plectranthus amboinicus (Lour.) Spreng. is a native Labiatae plant of Taiwan. The plants are
commonly used in Chinese folk medicine for the treatment of cough, fever, sore throats …

Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin‐induced orofacial nociception in rats

JG Chichorro, BB Lorenzetti… - British journal of …, 2004 - Wiley Online Library
This study characterises some of the mechanisms and mediators involved in the orofacial
nociception triggered by injection of formalin into the upper lip of the rat, by assessing the …

Mechanisms and mediators that drive arthritis pain

E Krustev, D Rioux, JJ McDougall - Current osteoporosis reports, 2015 - Springer
There are over 100 different types of arthritis and each can differ greatly in their aetiology
and pathophysiology; however, one characteristic that is common to all arthritic conditions is …