[HTML][HTML] Cerebral palsy—trends in epidemiology and recent development in prenatal mechanisms of disease, treatment, and prevention

M Stavsky, O Mor, SA Mastrolia, S Greenbaum… - Frontiers in …, 2017 - frontiersin.org
Cerebral palsy (CP) is the most common motor disability in childhood. This syndrome is the
manifestation of intrauterine pathologies, intrapartum complications, and the postnatal …

Early-onset neonatal sepsis

KA Simonsen, AL Anderson-Berry… - Clinical microbiology …, 2014 - Am Soc Microbiol
Early-onset sepsis remains a common and serious problem for neonates, especially preterm
infants. Group B streptococcus (GBS) is the most common etiologic agent, while Escherichia …

Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood

N Hagemeyer, KM Hanft, MA Akriditou, N Unger… - Acta …, 2017 - Springer
Whereas microglia involvement in virtually all brain diseases is well accepted their role in
the control of homeostasis in the central nervous system (CNS) is mainly thought to be the …

Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism

JT Morgan, G Chana, CA Pardo, C Achim… - Biological …, 2010 - Elsevier
BACKGROUND: In the neurodevelopmental disorder autism, several neuroimmune
abnormalities have been reported. However, it is unknown whether microglial somal volume …

Brain-immune interactions in perinatal hypoxic-ischemic brain injury

B Li, K Concepcion, X Meng, L Zhang - Progress in neurobiology, 2017 - Elsevier
Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Neurodevelopmental impairment in children after group B streptococcal disease worldwide: systematic review and meta-analyses

M Kohli-Lynch, NJ Russell, AC Seale… - Clinical Infectious …, 2017 - academic.oup.com
Background Survivors of infant group B streptococcal (GBS) disease are at risk of
neurodevelopmental impairment (NDI), a burden not previously systematically quantified …

Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism

J Sugimoto, AM Romani… - The Journal of …, 2012 - journals.aai.org
MgSO 4 exposure before preterm birth is neuroprotective, reducing the risk of cerebral palsy
and major motor dysfunction. Neonatal inflammatory cytokine levels correlate with …

[HTML][HTML] Microglial dynamics during human brain development

DA Menassa, D Gomez-Nicola - Frontiers in immunology, 2018 - frontiersin.org
Microglial cells are thought to colonize the human cerebrum between the 4th and 24th
gestational weeks. Rodent studies have demonstrated that these cells originate from yolk …

The yin and yang of microglia

M Czeh, P Gressens, AM Kaindl - Developmental neuroscience, 2011 - karger.com
Microglia, the resident immune cells of the mammalian central nervous system (CNS), play a
pivotal role in both physiological and pathological conditions such as the restoration of CNS …

Infection-induced inflammation and cerebral injury in preterm infants

T Strunk, T Inder, X Wang, D Burgner… - The Lancet infectious …, 2014 - thelancet.com
Preterm birth and infectious diseases are the most common causes of neonatal and early
childhood deaths worldwide. The rates of preterm birth have increased over recent decades …