[HTML][HTML] Targeting breast cancer stem cells
The potential roles of breast cancer stem cells (BCSCs) in tumor initiation and recurrence
have been recognized for many decades. Due to their strong capacity for self-renewal and …
have been recognized for many decades. Due to their strong capacity for self-renewal and …
Metabolic dependencies and targets in ovarian cancer
Reprogramming of cellular metabolism is a hallmark of cancer. Cancer cells undergo
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …
The effects of omega-3 polyunsaturated fatty acids on breast cancer as a preventive measure or as an adjunct to conventional treatments
MH Theinel, MP Nucci, AH Alves, OFM Dias… - Nutrients, 2023 - mdpi.com
In order to understand how omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements
affect breast cancer prevention and treatment, a systematic review of articles published in …
affect breast cancer prevention and treatment, a systematic review of articles published in …
[HTML][HTML] The emerging role of PPAR-alpha in breast cancer
Z Qian, L Chen, J Liu, Y Jiang, Y Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer has been confirmed to have lipid disorders in the tumour microenvironment.
Peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated …
Peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated …
Three-dimensional spheroid culture of dental pulp-derived stromal cells enhance their biological and regenerative properties for potential therapeutic applications
S Raik, P Sharma, S Kumar, V Rattan, A Das… - … International Journal of …, 2023 - Elsevier
Mesenchymal stem/stromal cell (MSC) spheroids generated in a three-dimensional (3D)
culture system serve as a surrogate model that maintain stem cell characteristics since these …
culture system serve as a surrogate model that maintain stem cell characteristics since these …
Metabolic plasticity of cancer stem cells in response to Microenvironmental cues
Simple Summary Accumulating evidence indicates the existence of cancer stem cells
(CSCs) sub-populations which fuel cancer growth and maintain stemness in different …
(CSCs) sub-populations which fuel cancer growth and maintain stemness in different …
[HTML][HTML] The deubiquitinase USP13 maintains cancer cell stemness by promoting FASN stability in small cell lung cancer
USP13 is significantly amplified in over 20% of lung cancer patients and critical for tumor
progression. However, the functional role of USP13 in small cell lung cancer (SCLC) …
progression. However, the functional role of USP13 in small cell lung cancer (SCLC) …
[HTML][HTML] Effects of ω-3 fatty acids and ratio of ω-3/ω-6 for health promotion and disease prevention
A Mukhametov, M Yerbulekova… - Food Science and …, 2022 - SciELO Brasil
Awareness of the role of essential fatty acids in human health and disease prevention has
been increasing among the population over the past decades. It is known that the positive …
been increasing among the population over the past decades. It is known that the positive …
[HTML][HTML] Spatholobus suberectus inhibits lipogenesis and tumorigenesis in triple-negative breast cancer via activation of AMPK-ACC and K-Ras-ERK signaling …
X Zeng, G Gong, K Ganesan, Y Wen, Q Liu… - Journal of Traditional …, 2023 - Elsevier
Background and aim Triple-negative breast cancer (TNBC) is a highly invasive type of
breast cancer with a poor prognosis. Currently, there are no effective management …
breast cancer with a poor prognosis. Currently, there are no effective management …
Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology
The initial excitement generated more than two decades ago by the discovery of drugs
targeting fatty acid synthase (FASN)‐catalyzed de novo lipogenesis for cancer therapy was …
targeting fatty acid synthase (FASN)‐catalyzed de novo lipogenesis for cancer therapy was …