Wearable electrochemical sensors capable of noninvasive monitoring of chemical markers
represent a rapidly emerging digital-health technology. Recent advances toward wearable …

The purpose of this comprehensive review is to describe various aspects of crisis of opioid
use in the United States. The obstacles that must be surmounted are primarily inappropriate …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Chronic pain and prescription opioid abuse are extremely prevalent both in this country and
worldwide. Consequences of opioid misuse can be life-threatening with significant morbidity …

OBJECTIVE: To develop evidence-based clinical practice guidelines for interventional
techniques in the diagnosis and treatment of chronic spinal pain. METHODOLOGY …

10, 30, 34, 39, 41-43, 61, 71-73, 77, 78). According to the Diagnostic and Statistical Manual
of Mental Disorders, Fourth Edition (DSM-IV), diagnostic criteria for substance abuse include …

The concurrent use of opioids, benzodiazepines (BZDs), and/or alcohol poses a formidable
challenge for clinicians who manage chronic pain. While the escalating use of opioid …

Background: The epidemic of medical use and abuse of opioid analgesics is linked to the
economic burden of opioid-related abuse and fatalities in the United States. Multiple studies …

This is an article in the Core Entrustables in Clinical Pharmacology series that describes
opioid therapy in acute and chronic pain. Opioid use during surgical procedures or …

Background Chronic pain is commonly treated with analgesic medication. Non‐adherence
to prescribed pain medication is very common and may result in sub‐optimal treatment …