Lipid-based nanoparticles for drug/gene delivery: An overview of the production techniques and difficulties encountered in their industrial development

M Mehta, TA Bui, X Yang, Y Aksoy, EM Goldys… - ACS Materials …, 2023 - ACS Publications
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …

[HTML][HTML] Intelligent control of nanoparticle synthesis on microfluidic chips with machine learning

X Chen, H Lv - NPG Asia Materials, 2022 - nature.com
Nanoparticles play irreplaceable roles in optoelectronic sensing, medical therapy, material
science, and chemistry due to their unique properties. There are many synthetic pathways …

Lipid nanoparticles for siRNA delivery in cancer treatment

SH El Moukhtari, E Garbayo, A Amundarain… - Journal of Controlled …, 2023 - Elsevier
RNA-based therapies, and siRNAs in particular, have attractive therapeutic potential for
cancer treatment due to their ability to silence genes that are imperative for tumor …

Lipid nanoparticle technologies for nucleic acid delivery: A nanoarchitectonics perspective

AR Ferhan, S Park, H Park, H Tae… - Advanced Functional …, 2022 - Wiley Online Library
Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …

[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment

P Graván, A Aguilera-Garrido, JA Marchal… - Advances in Colloid and …, 2023 - Elsevier
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …

Recent advances on chitosan as an adjuvant for vaccine delivery

I Dmour, N Islam - International Journal of Biological Macromolecules, 2022 - Elsevier
Chitosan (CS) is a natural polymer derived from chitin that has wide applications in drugs,
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …

[HTML][HTML] Recent developments in microfluidic technology for synthesis and toxicity-efficiency studies of biomedical nanomaterials

A Bendre, MP Bhat, KH Lee, T Altalhi, MA Alruqi… - Materials Today …, 2022 - Elsevier
Microfluidic technology is a relatively new field among the various conventional bulk
techniques employed for nanomaterial synthesis. Nanoparticles (NPs) produced using such …

Microfluidic technologies for nanoparticle formation

F Tian, L Cai, C Liu, J Sun - Lab on a Chip, 2022 - pubs.rsc.org
Functional nanoparticles (NPs) hold immense promise in diverse fields due to their unique
biological, chemical, and physical properties associated with size or morphology …

[HTML][HTML] An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates

M Ripoll, MC Bernard, C Vaure, E Bazin… - Biomaterials, 2022 - Elsevier
The mRNA vaccine technology has promising applications to fight infectious diseases as
demonstrated by the licensing of two mRNA-based vaccines, Comirnaty®(Pfizer/BioNtech) …

[HTML][HTML] Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application

BG Carvalho, BT Ceccato, M Michelon, SW Han… - Pharmaceutics, 2022 - mdpi.com
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …