[HTML][HTML] Microfluidics technology for the design and formulation of nanomedicines

E Jaradat, E Weaver, A Meziane, DA Lamprou - Nanomaterials, 2021 - mdpi.com
In conventional drug administration, drug molecules cross multiple biological barriers,
distribute randomly in the tissues, and can release insufficient concentrations at the desired …

Lipid based nanocarriers: Production techniques, concepts, and commercialization aspect

R Kumar, DS Dkhar, R Kumari, S Mahapatra… - Journal of Drug Delivery …, 2022 - Elsevier
Over the past decade, compared to all other macromolecules lipid-based nanocarriers have
proven to be an excellent carrier and delivery system for various pharmaceutical drugs of …

[HTML][HTML] Microfluidics for personalized drug delivery

SE Alavi, S Alharthi, SF Alavi, SZ Alavi, GE Zahra… - Drug Discovery …, 2024 - Elsevier
This review highlights the transformative impact of microfluidic technology on personalized
drug delivery. Microfluidics addresses issues in traditional drug synthesis, providing precise …

Nanotechnology in coronary heart disease

J Guo, H Wang, Y Li, S Zhu, H Hu, Z Gu - Acta Biomaterialia, 2023 - Elsevier
Coronary heart disease (CHD) is one of the major causes of death and disability worldwide,
especially in low-and middle-income countries and among older populations. Conventional …

[HTML][HTML] Serum extracellular vesicles for delivery of CRISPR-CAS9 ribonucleoproteins to modify the dystrophin gene

N Majeau, A Fortin-Archambault, C Gérard… - Molecular Therapy, 2022 - cell.com
Extracellular vesicles (EVs) mediate intercellular biomolecule exchanges in the body,
making them promising delivery vehicles for therapeutic cargo. Genetic engineering by the …

Nickel oxide nanoparticle synthesis and photocatalytic applications: evolution from conventional methods to novel microfluidic approaches

J Mou, Y Ren, J Wang, C Wang, Y Zou, K Lou… - Microfluidics and …, 2022 - Springer
Nickel oxide (NiO) nanoparticles are essential to developing a wide range of important
industrial products, examples of which include electrodes, catalysts, and sensors, leading to …

Chemistry and art of developing lipid nanoparticles for biologics delivery: focus on development and scale-up

R John, J Monpara, S Swaminathan, R Kalhapure - Pharmaceutics, 2024 - mdpi.com
Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

[HTML][HTML] Evaluating how cationic lipid affects mRNA-LNP physical properties and biodistribution

C Guéguen, TB Chimol, M Briand, K Renaud… - European Journal of …, 2024 - Elsevier
RNA therapeutics represents a powerful strategy for diseases where other approaches have
failed, especially given the recent successes of mRNA vaccines against the coronavirus …

Nanoemulsions embedded in alginate beads as bioadhesive nanocomposites for intestinal delivery of the anti-inflammatory drug tofacitinib

V Andretto, G Taurino, G Guerriero, H Guérin… - …, 2023 - ACS Publications
Oral administration of nanoparticles (NPs) is a promising strategy to overcome solubility and
stability issues of many active compounds. However, this route faces major obstacles related …

Optimization of large-scale manufacturing of biopolymeric and lipid nanoparticles using microfluidic swirl mixers

MA Tomeh, MH Mansor, R Hadianamrei, W Sun… - International Journal of …, 2022 - Elsevier
Nanoparticles (NPs) have great potential as efficient drug delivery systems (DDSs) that have
been widely used in cancer therapy and vaccines especially in the past decade. The rise in …