mRNA vaccines in the prevention and treatment of diseases

Y Gu, J Duan, N Yang, Y Yang, X Zhao - MedComm, 2022 - Wiley Online Library
Messenger ribonucleic acid (mRNA) vaccines made their successful public debut in the
effort against the COVID‐19 outbreak starting in late 2019, although the history of mRNA …

Microfluidic preparation of optical sensors for biomedical applications

Q Wang, C Wang, X Yang, J Wang, Z Zhang… - Smart …, 2023 - Wiley Online Library
Optical biosensors are platforms that translate biological information into detectable optical
signals, and have extensive applications in various fields due to their characteristics of high …

[HTML][HTML] Microfluidic formulation of DNA-loaded multicomponent lipid nanoparticles for gene delivery

E Quagliarini, S Renzi, L Digiacomo, F Giulimondi… - Pharmaceutics, 2021 - mdpi.com
In recent years, lipid nanoparticles (LNPs) have gained considerable attention in numerous
research fields ranging from gene therapy to cancer immunotherapy and DNA vaccination …

Microfluidics for development of lipid nanoparticles: paving the way for nucleic acids to the clinic

MS Ali, N Hooshmand, M El-Sayed… - ACS Applied Bio …, 2021 - ACS Publications
Nucleic acid therapeutics hold an unprecedented promise toward treating many challenging
diseases; however, their use is hampered by delivery issues. Microfluidics, dealing with …

[HTML][HTML] Microfluidic-based technologies for diagnosis, prevention, and treatment of COVID-19: recent advances and future directions

EA Tarim, M Anil Inevi, I Ozkan, S Kecili, E Bilgi… - Biomedical …, 2023 - Springer
The COVID-19 pandemic has posed significant challenges to existing healthcare systems
around the world. The urgent need for the development of diagnostic and therapeutic …

[HTML][HTML] A timescale-guided microfluidic synthesis of tannic acid-FeIII network nanocapsules of hydrophobic drugs

Y Shen, SA Yuk, S Kwon, H Tamam, Y Yeo… - Journal of Controlled …, 2023 - Elsevier
Many drugs are poorly water-soluble and suffer from low bioavailability. Metal-phenolic
network (MPN), a hydrophilic thin layer such as tannic acid (TA)-Fe III network, has been …

Formation of protein nanoparticles in microdroplet flow reactors

Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo… - ACS …, 2023 - ACS Publications
Nanoparticles are increasingly being used for biological applications, such as drug delivery
and gene transfection. Different biological and bioinspired building blocks have been used …

Fabrication of ZnO/Ag and ZnO/Fe nanoparticles with immobilised peroxidase as a biocatalyst for photodegradation of ibuprofen

O Długosz, K Szostak, J Matysik, W Matyjasik… - Sustainable Materials …, 2023 - Elsevier
This paper presents the preparation of a photocatalyst based on ZnO nanoparticles modified
with silver and iron ions and peroxidase (ZnO/Ag/POX NPs and ZnO/Fe/POX NPs). The …

Microfluidic mixing as platform technology for production of chitosan nanoparticles loaded with different macromolecules

A Greco, B Gabold, S Chen, X Wang, Z Xu… - European Journal of …, 2023 - Elsevier
In recent decades, biotechnological drugs have emerged as relevant therapeutic tools.
However, therapeutic molecules can exert their activity only if properly formulated and …

Microfluidic formulation of curcumin-loaded multiresponsive gelatin nanoparticles for anticancer therapy

Y Xia, R Xu, S Ye, J Yan, P Kumar… - … Science & Engineering, 2023 - ACS Publications
Current anticancer research shows that a combination of multiple treatment methods can
greatly improve the killing of tumor cells. Using the latest microfluidic swirl mixer technology …