Role of AMP deaminase in diabetic cardiomyopathy

T Miura, H Kouzu, M Tanno, Y Tatekoshi… - Molecular and Cellular …, 2024 - Springer
Diabetes mellitus is one of the major causes of ischemic and nonischemic heart failure.
While hypertension and coronary artery disease are frequent comorbidities in patients with …

Downregulation of extramitochondrial BCKDH and its uncoupling from AMP deaminase in type 2 diabetic OLETF rat hearts

T Ogawa, H Kouzu, A Osanami… - Physiological …, 2023 - Wiley Online Library
Systemic branched‐chain amino acid (BCAA) metabolism is dysregulated in
cardiometabolic diseases. We previously demonstrated that upregulated AMP deaminase 3 …

Metabolic signature of energy metabolism alterations and excess nitric oxide production in culture media correlate with low human embryo quality and unsuccessful …

R Pallisco, G Lazzarino, G Bilotta, F Marroni… - International Journal of …, 2023 - mdpi.com
Notwithstanding the great improvement of ART, the overall rate of successful pregnancies
from implanted human embryos is definitely low. The current routine embryo quality …

[HTML][HTML] So close, yet so far away: the relationship between MAM and cardiac disease

B Lu, X Chen, Y Ma, M Gui, L Yao, J Li… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Mitochondria-associated membrane (MAM) serve as crucial contact sites between
mitochondria and the endoplasmic reticulum (ER). Recent research has highlighted the …

Adenosine monophosphate deaminase in the endoplasmic reticulum–mitochondria interface promotes mitochondrial Ca2+ overload in type 2 diabetes rat hearts

A Osanami, T Sato, Y Toda, M Shimizu… - Journal of Diabetes …, 2023 - Wiley Online Library
Abstract Aims/Introduction We previously showed that upregulation of myocardial adenosine
monophosphate deaminase (AMPD) is associated with pressure overload‐induced diastolic …

Identification and analysis of hub genes of hypoxia-immunity in type 2 diabetes mellitus

J Li, N Yan, X Li, S He, X Yu - Frontiers in Genetics, 2023 - frontiersin.org
The chronic metabolic disease named type 2 diabetes (T2D) accounts for over 90% of
diabetes mellitus. An increasing number of evidences have revealed that hypoxia has a …

[HTML][HTML] The Good and the Bad: The Bifunctional Enzyme Xanthine Oxidoreductase in the Production of Reactive Oxygen Species

BC Seychell, M Vella, GJ Hunter, T Hunter - 2023 - intechopen.com
Xanthine oxidoreductase (XOR) is a molybdoflavin enzyme which occurs in two forms; the
reduced form known as xanthine dehydrogenase (XDH, EC 1.17. 1.4) and the oxidised form …

[PDF][PDF] AMP deaminase in the ER-mitochondria interface promotes mitochondrial Ca2+ overload in type 2 diabetic rat hearts

A Osanami, T Sato, Y Toda, M Shimizu, A Kuno… - 2023 - sapmed.repo.nii.ac.jp
ABSTRACT Aims/Introduction: We previously showed that upregulation of myocardial AMP
deaminase (AMPD) is associated with pressure overload-induced diastolic dysfunction in …

[PDF][PDF] OxiSelect™ Advanced Glycation End Product (AGE) Competitive ELISA Kit, Trial Size

P Manual - cellbiolabs.com
The non-enzymatic reaction of reducing carbohydrates with lysine side chains and N-
terminal amino groups of macromolecules (proteins, phospholipids and nucleic acids) is …

[PDF][PDF] OxiSelect™ Advanced Glycation End Product (AGE) Competitive ELISA Kit

P Manual - cellbiolabs.com
The non-enzymatic reaction of reducing carbohydrates with lysine side chains and N-
terminal amino groups of macromolecules (proteins, phospholipids and nucleic acids) is …