Globally, depression is a leading cause of disability and has remained so for decades.
Antidepressant medications have suboptimal outcomes and are too frequently associated …

Taurine is a sulfur-containing amino acid and known as semi-essential in mammals and is
produced chiefly by the liver and kidney. It presents in different organs, including retina …

Glycine is a major neurotransmitter involved in several fundamental neuronal processes.
The identity of the metabotropic receptor mediating slow neuromodulatory effects of glycine …

Accumulating evidence has demonstrated that oxidative stress is associated with
depression. Our present study aimed at investigating the antidepressant effect and the …

Altered neurogenesis is suggested to be involved in the onset of brain diseases, including
mental disorders and neurodegenerative diseases. Neurotrophic factors are well known for …

Taurine is a key functional amino acid with many functions in the nervous system. The
effects of taurine on cognitive function have aroused increasing attention. First, the …

Taurine is the most abundant free amino acid in the body, and is mainly derived from the
diet, but can also be produced endogenously from cysteine. It plays multiple essential roles …

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often
associated with debilitating symptoms and adverse multisystem consequences. We obtain …

Purpose: It is revealed that Xiaoyaosan could reduce glutamate level in the hippocampus of
depressed rats, whose metabolism leads to the pathophysiology of depression. However …

Taurine is considered the most abundant free amino acid in the brain. Even though there are
endogenous mechanisms for taurine production in neural cells, an exogenous supply of …