The Interaction between the Host Genome, Epigenome, and the Gut–Skin Axis Microbiome in Atopic Dermatitis

R Pessôa, PB Clissa, SS Sanabani - International Journal of Molecular …, 2023 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease that occurs in genetically
predisposed individuals. It involves complex interactions among the host immune system …

[HTML][HTML] Epigenetic control of inflammation in Atopic Dermatitis

S Akhtar, RKME Alsayed, F Ahmad… - Seminars in Cell & …, 2024 - Elsevier
Atopic dermatitis (AD), also known as atopic eczema, is a common but also complex chronic,
itchy skin condition with underlying inflammation of the skin. This skin ailment is prevalent …

Mechanism underlying polyvalent IgG-induced regulatory T cell activation and its clinical application: anti-idiotypic regulatory T cell theory for immune tolerance

JR Victor, DH Nahm - Frontiers in Immunology, 2023 - frontiersin.org
The regulatory T (Treg) cells constitute a functionally defined subpopulation of T cells that
modulate the immune system and maintain immune tolerance through suppression of the …

IgG from Dermatophagoides pteronyssinus (Der p)-atopic individuals modulates non-atopic thymic B cell phenotype (alfa-4/beta-7) and cytokine production (IFN-γ, IL …

DT de-Apoena Reche, NR Machado, BO Fagundes… - Scientific Reports, 2024 - nature.com
Studies about thymic B cells are scarce in the literature, but it was suggested that they can
exert modulatory and regulatory functions on the immune system. Thymic B cells can play …

IgG from patients with mild or severe COVID‑19 reduces the frequency and modulates the function of peripheral mucosal-associated invariant T cells in PBMCs from …

NR Machado, BO Fagundes… - Biomedical …, 2023 - spandidos-publications.com
Lower levels of peripheral mucosal‑associated invariant T (MAIT) cells have been observed
in the peripheral blood of patients with severe coronavirus disease 2019 (COVID‑19) …

Deciphering epigenetic regulations in the inflammatory pathways of atopic dermatitis

AJ da Silva Duarte, SS Sanabani - Life Sciences, 2024 - Elsevier
Atopic dermatitis, commonly referred to as atopic eczema, is a persistent inflammatory skin
disorder that predominantly manifests in children but may endure into adulthood. Its clinical …

[HTML][HTML] Immune modulation and possible pathological implications mediated by naturally produced immunoglobulin G idiotypes: from historical to recent experimental …

L Santander, NR Machado, BO Fagundes… - Clinical and …, 2024 - ncbi.nlm.nih.gov
Since the 1950s decade, it has been suggested that a naturally produced or induced
repertoire of immunoglobulin G (IgG) idiotypes may exert some immunoregulatory functions …

IgG from individuals without atopy arising as mediators of a nonatopic profile in human peripheral CD4+ T cells

FRM Cunha, BO Fagundes… - Annals of allergy …, 2024 - pubmed.ncbi.nlm.nih.gov
IgG from individuals without atopy arising as mediators of a nonatopic profile in human
peripheral CD4+ T cells IgG from individuals without atopy arising as mediators of a …

[PDF][PDF] Lucas Santander1, Nicolle Rakanidis Machado2, Beatriz Oliveira Fagundes2

JR Victor - ecevr.org
Since the 1950s decade, it has been suggested that a naturally produced or induced
repertoire of immunoglobulin G (IgG) idiotypes may exert some immunoregulatory functions …