Bispecific antibodies: from research to clinical application
J Ma, Y Mo, M Tang, J Shen, Y Qi, W Zhao… - Frontiers in …, 2021 - frontiersin.org
Bispecific antibodies (BsAbs) are antibodies with two binding sites directed at two different
antigens or two different epitopes on the same antigen. The clinical therapeutic effects of …
antigens or two different epitopes on the same antigen. The clinical therapeutic effects of …
Rheumatoid arthritis: the impact of mental health on disease: a narrative review
MN Lwin, L Serhal, C Holroyd, CJ Edwards - Rheumatology and therapy, 2020 - Springer
Over 60% of rheumatoid arthritis (RA) patients achieve a good response after 12 months of
treatment when following the European league against rheumatism (EULAR) guidelines for …
treatment when following the European league against rheumatism (EULAR) guidelines for …
Sinomenine inhibits the progression of rheumatoid arthritis by regulating the secretion of inflammatory cytokines and monocyte/macrophage subsets
W Liu, Y Zhang, W Zhu, C Ma, J Ruan, H Long… - Frontiers in …, 2018 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthropathy associated with
articular damage and attendant comorbidities. Even although RA treatment has advanced …
articular damage and attendant comorbidities. Even although RA treatment has advanced …
2018 update of the APLAR recommendations for treatment of rheumatoid arthritis
Aim To update recommendations based on current best evidence concerning the treatment
of rheumatoid arthritis (RA), focusing particularly on the role of targeted therapies, to inform …
of rheumatoid arthritis (RA), focusing particularly on the role of targeted therapies, to inform …
Melatonin attenuates TNF‐α and IL‐1β expression in synovial fibroblasts and diminishes cartilage degradation: Implications for the treatment of rheumatoid arthritis
CC Huang, CH Chiou, SC Liu, SL Hu… - Journal of pineal …, 2019 - Wiley Online Library
The hormone melatonin has many properties, including antioxidant, anti‐inflammatory, and
immunomodulatory effects. Melatonin has been demonstrated to be beneficial in several …
immunomodulatory effects. Melatonin has been demonstrated to be beneficial in several …
Treatment with biologicals in rheumatoid arthritis: an overview
P Rein, RB Mueller - Rheumatology and therapy, 2017 - Springer
Management and therapy of rheumatoid arthritis (RA) has been revolutionized by the
development and approval of the first biological disease-modifying antirheumatic drugs …
development and approval of the first biological disease-modifying antirheumatic drugs …
Immunological adaptations in pregnancy that modulate rheumatoid arthritis disease activity
F Förger, PM Villiger - Nature Reviews Rheumatology, 2020 - nature.com
During pregnancy, the fetus that grows within the maternal uterus is not rejected by the
maternal immune system. To enable both tolerance towards the fetus and defence against …
maternal immune system. To enable both tolerance towards the fetus and defence against …
[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …
maintain, and restore healthy functioning of nearly every physiological system of the human …
[HTML][HTML] Microneedles-based drug delivery strategies: A breakthrough approach for the management of pain
S Priya, G Singhvi - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Pain is a personalized event or body alarm system that can limit a patient's activities and
lead to negative repercussions. The commercially available conventional treatment …
lead to negative repercussions. The commercially available conventional treatment …
An association of gut microbiota with different phenotypes in Chinese patients with rheumatoid arthritis
We aimed to investigate the association of gut microbiota with disease activity, inflammatory
parameters, and auto-antibodies profile in rheumatoid arthritis (RA). A total of 138 RA …
parameters, and auto-antibodies profile in rheumatoid arthritis (RA). A total of 138 RA …