Real-world therapeutic response and tyrosine kinase inhibitor discontinuation in chronic phase-chronic myeloid leukemia: data from the French observatory

S Saugues, C Lambert, E Daguenet, HJ Ansah… - Annals of …, 2022 - Springer
Guidelines for tyrosine kinase inhibitor (TKI)-treated chronic phase-chronic myeloid
leukemia (CML) management are essentially based on data from clinical research trials; …

Higher red blood cell distribution width is a poor prognostic factor for patients with chronic myeloid leukemia

T Li, X Li, H Chen, KZ Huang, Q Xie, HY Ge… - Cancer Management …, 2021 - Taylor & Francis
Purpose Red blood cell distribution width (RDW) has been considered as a potential
indicator of the effects of treatment or as a prognostic indicator for various malignancies …

[HTML][HTML] The Contemporary Role of Hematopoietic Stem Cell Transplantation in the Management of Chronic Myeloid Leukemia: Is It the Same in All Settings?

I Elmakaty, G Saglio, M Al-Khabori, A Elsayed… - Cancers, 2024 - mdpi.com
Simple Summary This review explores the use of hematopoietic stem cell transplantation
(HSCT) as a treatment option for chronic myeloid leukemia (CML) patients. While CML …

Mechanism of procyanidin b2 in the treatment of chronic myeloid leukemia based on integrating network pharmacology and molecular docking

HX Li, YX Jing, YH Chai, XH Sun, XX He… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Objective: To study the pharmacological mechanism of procyanidin B2 (PCB2) on chronic
myeloid leukemia (CML) by integrating network pharmacological methods systematically …

CD99 in malignant hematopoiesis

A Ali, VP Vaikari, H Alachkar - Experimental hematology, 2022 - exphem.org
The CD99 gene encodes a transmembrane protein that is involved in cell differentiation,
adhesion, migration, and protein trafficking. CD99 is differentially expressed on the surface …

Design, semi-synthesis and examination of new gypsogenin derivatives against leukemia via Abl tyrosine kinase inhibition and apoptosis induction

NG Ulusoy, S Emirdağ, E Sözer, MO Radwan… - International Journal of …, 2022 - Elsevier
Chronic myelogenous leukemia (CML) is characterized by Philadelphia translocation arising
from Bcr-Abl fusion gene, which encodes abnormal oncoprotein showing tyrosine kinase …

[HTML][HTML] Sulfurtransferases and cystathionine beta-synthase expression in different human leukemia cell lines

H Jurkowska, M Wróbel, E Jasek-Gajda, L Rydz - Biomolecules, 2022 - mdpi.com
The studies concerned the expression of sulfurtransferases and cystathionine beta-synthase
in six human leukemia cell lines: B cell acute lymphoblastic leukemia-B-ALL (REH cells), T …

[HTML][HTML] Nanotechnology in leukemia: diagnosis, efficient-targeted drug delivery, and clinical trials

MM Salama, NM Aborehab, NM El Mahdy… - European Journal of …, 2023 - Springer
Leukemia is a group of malignant disorders which affect the blood and blood-forming tissues
in the bone marrow, lymphatic system, and spleen. Many types of leukemia exist; thus, their …

[HTML][HTML] A brief overview of antitumoral actions of bruceine D

ZW Sin, V Bhardwaj, AK Pandey… - Exploration of targeted …, 2020 - ncbi.nlm.nih.gov
Cancer remains the second leading cause of mortality globally. In combating cancer,
conventional chemotherapy and/or radiotherapy are administered as first-line therapy …

[HTML][HTML] Dual-targeted therapy circumvents non-genetic drug resistance to targeted therapy

W Wang, Y Sun, X Liu, SK Kumar, F Jin, Y Dai - Frontiers in Oncology, 2022 - frontiersin.org
The introduction of various targeted agents into the armamentarium of cancer treatment has
revolutionized the standard care of patients with cancer. However, like conventional …