Free radical-mediated inflammatory processes account for a great portion of morbidity and
mortality in critically ill patients. The purpose of this study was to determine two plasma …

Purpose We tested the hypothesis that continued cigarette smoking exacerbates and its
cessation ameliorates progression of the early nephropathy of type 2 diabetes mellitus …

Diabetes mellitus is characterized by chronic hyperglycaemia and a significant risk of
developing micro-and macrovascular complications. Growing evidence suggests that …

Diabetic vascular complications are the most common cause of mortality and morbidity
worldwide, with numbers of affected individuals steadily increasing. Diabetic vascular …

Strong evidence implicates oxidative stress as a mediator of diabetes-induced
microvascular complications, including distal symmetric polyneuropathy. Dorsal root ganglia …

Background: Several studies suggested that women may be more susceptible to oxidative
damage induced by cigarette smoking, but the role of smoking status and antioxidant …

The role of oxidation injury as an important factor in the pathophysiology of cardiomyopathy
(CMP) has recently gained increasing interest. Semiquantitative analysis for isoprostane, 8 …

Background Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) is a lipoprotein-bound
enzyme that can release atherogenic isoprostanes from esterified phospholipids and that …

Background Diabetes mellitus in elderly represents an exceptional subset in the population
vulnerable to cardiovascular events. As aging, diabetes mellitus and hypertension share …

Background Emerging evidence showed the beneficial effect of acidic fibroblast growth
factor (aFGF) on heart diseases. The present study investigated whether non-mitogenic …