Executive summary Stroke is the second leading cause of death worldwide. The burden of
disability after a stroke is also large, and is increasing at a faster pace in low-income and …

The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …

Background DNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-
phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) …

Background The causes for immune-mediated inflammatory diseases (IMIDs) are diverse
and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to …

Objective To explore inequalities in human resources for health (HRH) in relation to all
cause and cause specific mortality globally in 1990-2019. Design Observational study …

Untreated osteochondral defects will develop into osteoarthritis, affecting patients' quality of
life. Since articular cartilage and subchondral bone exhibit distinct biological characteristics …

A novel fly ash-based composite material with multiple adsorption sites was synthesized to
remove Pb 2+, Cd 2+ and AsO 3 3− from wastewater. In a single pollutant system, when pH …

Background Parkinson's disease (PD) remains a common disabling progressive
neurodegenerative disorder. We aimed to report the prevalence, death and disability …

There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older
adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using …

Background The global production and use of plastic materials has increased dramatically
since the 1960s and there is increasing evidence of human health impacts related to …