The silent burden of non‐alcoholic fatty liver disease in the elderly: a global burden of disease analysis

P Danpanichkul, CH Ng, MD Muthiah… - Alimentary …, 2023 - Wiley Online Library
Background Non‐alcoholic fatty liver disease (NAFLD) represents a significant health threat
worldwide. The growing trend towards an aging population, along with an alarming rise in …

[HTML][HTML] Towards early detection of neurodegenerative diseases: A gut feeling

S Makdissi, BD Parsons, F Di Cara - Frontiers in cell and …, 2023 - frontiersin.org
The gastrointestinal tract communicates with the nervous system through a bidirectional
network of signaling pathways called the gut-brain axis, which consists of multiple …

[HTML][HTML] Exploring the impact of population ageing on the spread of emerging respiratory infections and the associated burden of mortality

S Møgelmose, K Neels, P Beutels, N Hens - BMC Infectious Diseases, 2023 - Springer
Background Increasing life expectancy and persistently low fertility levels have led to old
population age structures in most high-income countries, and population ageing is expected …

[HTML][HTML] Burden of cardiovascular disease among elderly: based on the Global Burden of Disease Study 2019

C Qu, S Liao, J Zhang, H Cao, H Zhang… - … Journal-Quality of …, 2024 - academic.oup.com
Background The burden of elderly cardiovascular disease (CVD) has received increasing
attention with population ageing worldwide. Aims We reported on the global CVD burden in …

Reprogramming iPSCs to study age-related diseases: models, therapeutics, and clinical trials

F Esteves, D Brito, AT Rajado, N Silva… - Mechanisms of Ageing …, 2023 - Elsevier
The unprecedented rise in life expectancy observed in the last decades is leading to a
global increase in the ageing population, and age-associated diseases became an …

[HTML][HTML] National and regional rates of chronic diseases and all-cause mortality in Saudi Arabia—Analysis of the 2018 household health survey data

MS Alzahrani, YS Alharthi, JK Aljamal… - International Journal of …, 2023 - mdpi.com
The disease burden and mortality were estimated in Saudi Arabia between 2010 and 2017
but were unknown in 2018. This study aims to assess the 2018 national and regional rates …

[HTML][HTML] Identification and experimental validation of ferroptosis-related gene lactotransferrin in age-related hearing loss

C Zeng, X Gu, Y Chen, Y Lin, J Chen… - Frontiers in Aging …, 2024 - frontiersin.org
Objective To reveal the relationship between ARHL and ferroptosis and screen ferroptosis-
related genes (FRGs) in ARHL. Methods Bioinformatics were used to analyze the hub genes …

[HTML][HTML] Does abdominal obesity increase all-cause, cardiovascular disease, and cancer mortality risks in older adults? A 10-year follow-up analysis

LAN Moura, V Pagotto, C Camargo Pereira… - Nutrients, 2022 - mdpi.com
There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older
adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using …

[HTML][HTML] Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review

M Knufinke, MR MacArthur, CY Ewald, SJ Mitchell - Frontiers in Aging, 2023 - frontiersin.org
With an increasing aging population, the burden of age-related diseases magnifies. To
alleviate this burden, geroprotection has been an area of intense research focus with the …

Physical activity, sedentary behaviour, and cognitive function among older adults: A bibliometric analysis from 2004 to 2024

Z Yang, P Hotterbeex, PJ Marent, E Cerin… - Ageing Research …, 2024 - Elsevier
Because of population ageing, there will be a vast increase in the prevalence of cognitive
decline and dementia. Physical activity and sedentary behaviour have been identified as …