The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy
D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
Abstract The international American Joint Committee on Cancer/Union for International
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
Candida albicans—The Virulence Factors and Clinical Manifestations of Infection
J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …
Immune crosstalk in cancer progression and metastatic spread: a complex conversation
H Garner, KE de Visser - Nature Reviews Immunology, 2020 - nature.com
Metastatic disease is responsible for approximately 90% of cancer deaths. For successful
dissemination and metastasis, cancer cells must evade detection and destruction by the …
dissemination and metastasis, cancer cells must evade detection and destruction by the …
IL-12, IL-23 and IL-17 in IBD: immunobiology and therapeutic targeting
AR Moschen, H Tilg, T Raine - Nature Reviews Gastroenterology & …, 2019 - nature.com
Abstract IL-12 and IL-23 are closely related cytokines with important roles in the regulation of
tissue inflammation. Converging evidence from studies in mice, human observational …
tissue inflammation. Converging evidence from studies in mice, human observational …
[HTML][HTML] Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies
Abstract Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of
intensive research because of its crucial role in the pathogenesis of different diseases …
intensive research because of its crucial role in the pathogenesis of different diseases …
[HTML][HTML] Focus: skin: current developments in the immunology of psoriasis
F Grän, A Kerstan, E Serfling, M Goebeler… - The Yale journal of …, 2020 - ncbi.nlm.nih.gov
Psoriasis is a frequent inflammatory skin disease. Fundamental research on the
pathogenesis of psoriasis has substantially increased our understanding of skin …
pathogenesis of psoriasis has substantially increased our understanding of skin …
Novel therapies for immune-mediated inflammatory diseases: what can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus …
The past three decades have witnessed remarkable advances in our ability to target specific
elements of the immune and inflammatory response, fuelled by advances in both …
elements of the immune and inflammatory response, fuelled by advances in both …
Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage
H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …
IL‐17 and IL‐22 in immunity: Driving protection and pathology
K Eyerich, V Dimartino, A Cavani - European journal of …, 2017 - Wiley Online Library
IL‐17 and IL‐22 are tissue‐signaling cytokines that favor protection and regeneration of
barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share …
barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share …
Selected cytokine pathways in rheumatoid arthritis
M Noack, P Miossec - Seminars in immunopathology, 2017 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction.
Cytokines play a key role in its pathogenesis. They contribute to the induction and …
Cytokines play a key role in its pathogenesis. They contribute to the induction and …