Usher syndrome (USH) is a rare, autosomal recessively inherited disorder resulting in a
combination of sensorineural hearing loss and a progressive loss of vision resulting from …

Background The pathophysiology of childhood food allergy (FA) and its natural history are
poorly understood. Clarification of the underlying mechanism may help identify novel …

Variability in response to short-acting β2-agonists (eg, albuterol) among patients with
asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to …

Background Refractory asthma (RA) remains poorly controlled, resulting in high health care
utilization despite guideline-based therapies. Patients with RA manifest higher neutrophilia …

Background Thermal stress in subtropical regions is a major limiting factor in beef cattle
production systems with around $369 million being lost annually due to reduced …

Background Disturbance of mucociliary clearance is an important factor in the pathogenesis
of asthma. We hypothesized that common variants in genes responsible for ciliary function …

Background: Forkhead box J1 (FOXJ1) plays pivotal roles in motile cilia formation. However,
it remains unclear whether abnormal expression or localization of FOXJ1 in nasal mucosa …

Background Gene expression patterns (particularly, cilia-associated genes) of nasal
mucosa, the first-line defense system, in allergic rhinitis (AR) are not well understood …

Background Allergic rhinitis (AR) is believed to be a complex genetic disease. The last
decade has been marked by the publication of more than 20 genome-wide association …

Background A positional cloning study of bronchial hyper-responsiveness (BHR) at the
17p11 locus in the French Epidemiological study on the Genetics and Environment of …