Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing Research Reviews, 2021 - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Immunology of aging: the birth of inflammaging

T Fulop, A Larbi, G Pawelec, A Khalil, AA Cohen… - Clinical reviews in …, 2021 - Springer
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

[HTML][HTML] Immunosenescence, aging and successful aging

Y Wang, C Dong, Y Han, Z Gu, C Sun - Frontiers in immunology, 2022 - frontiersin.org
Aging induces a series of immune related changes, which is called immunosenescence,
playing important roles in many age-related diseases, especially neurodegenerative …

Inflammaging: The ground for sarcopenia?

Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

Immunosenescence and COVID-19

JM Witkowski, T Fulop, E Bryl - Mechanisms of ageing and development, 2022 - Elsevier
Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …

Aging and chronic inflammation: highlights from a multidisciplinary workshop

D Saavedra, AL Añé-Kourí, N Barzilai, C Caruso… - Immunity & …, 2023 - Springer
Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

Cellular senescence: pathogenic mechanisms in lung fibrosis

T Parimon, MS Hohmann, C Yao - International journal of molecular …, 2021 - mdpi.com
Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …

Physical activity and nutritional influence on immune function: an important strategy to improve immunity and health status

T Shao, HK Verma, B Pande, V Costanzo, W Ye… - Frontiers in …, 2021 - frontiersin.org
Physical activity (PA) and nutrition are the essential components of a healthy lifestyle, as
they can influence energy balance, promote functional ability of various systems and …

[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Immunosenescence and altered vaccine efficiency in older subjects: A myth difficult to change

T Fulop, A Larbi, G Pawelec, AA Cohen, G Provost… - Vaccines, 2022 - mdpi.com
Organismal ageing is associated with many physiological changes, including differences in
the immune system of most animals. These differences are often considered to be a key …