Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria
are essential organelles responsible for numerous physiologic processes, such as energy …

Flavonoids are a class of bioactive phytochemicals containing a core 2-phenylchromone
skeleton and are widely found in fruits, vegetables, and herbs. Such natural compounds …

Disulfiram (DSF), a drug for alcohol withdrawal, has attracted extensive scientific attention
due to its potential to treat cancer. The metabolite of DSF, diethyl dithiocarbamate (DDTC) …

Disulfidptosis is a newly-identified non-programmed cell death mode with tight associations
with glucose metabolism. Elevated glycolysis is an important metabolic feature of tumor …

Ferroptosis, a novel form of cell death regulation, was identified in 2012. It is characterized
by unique features that differentiate it from other types of cell death, including necrosis …

Gastric cancer is a common cancer worldwide, particularly in East Asia. Chemotherapy is
used in adjuvant or palliative therapies for gastric cancer. However, subsequent …

Background Acute-on-chronic liver failure (ACLF) constitutes a prevalent manifestation of
liver failure within clinical settings. This condition manifests swiftly and is characterized by an …

Background Gastric cancer (GC) remains a malignant tumor with high morbidity and
mortality, accounting for approximately 1,080,000 diagnosed cases and 770,000 deaths …

In conjunction with previous studies, we have noted that ferroptosis, as an emerging mode of
regulated cell death (RCD), is intimately related to anthracycline pharmacotherapy. Not only …

Background: Disulfidptosis is a novel form of programmed cell death that unveils promising
avenues for the exploration of tumor treatment modalities. Gastric cancer (GC) is a malignant …