[HTML][HTML] A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors

AR Patten, CJ Fontaine, BR Christie - Frontiers in pediatrics, 2014 - frontiersin.org
Prenatal ethanol exposure (PNEE) has been linked to widespread impairments in brain
structure and function. There are a number of animal models that are used to study the …

Human placenta: a human organ for developmental toxicology research and biomonitoring

P Myllynen, M Pasanen, O Pelkonen - Placenta, 2005 - Elsevier
Pregnant mothers are exposed to a wide variety of foreign chemicals. This exposure is most
commonly due to maternal medication, lifestyle factors, such as smoking, drug abuse, and …

Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models

J Gil-Mohapel, F Boehme, L Kainer, BR Christie - Brain research reviews, 2010 - Elsevier
Prenatal ethanol exposure is invariably detrimental to the developing central nervous
system and the hippocampus is particularly sensitive to the teratogenic effects of ethanol …

Species differences in pharmacokinetics and drug teratogenesis.

H Nau - Environmental health perspectives, 1986 - ehp.niehs.nih.gov
Interspecies differences in regard to the teratogenicity of drugs can be the result of differing
pharmacokinetic processes that determine the crucial concentration-time relationships in the …

Magnetic resonance microscopy defines ethanol‐induced brain abnormalities in prenatal mice: Effects of acute insult on gestational day 7

EA Godin, SK O'Leary‐Moore, AA Khan… - Alcoholism: clinical …, 2010 - Wiley Online Library
Background: This magnetic resonance microscopy (MRM)‐based report is the second in a
series designed to illustrate the spectrum of craniofacial and central nervous system (CNS) …

[HTML][HTML] Epigallocatechin gallate ameliorates the effects of prenatal alcohol exposure in a fetal alcohol spectrum disorder-like mouse model

L Almeida-Toledano, V Andreu-Fernández… - International Journal of …, 2021 - mdpi.com
Fetal alcohol spectrum disorder is the main preventable cause of intellectual disability in the
Western world. Although binge drinking is the most studied prenatal alcohol exposure …

I. Functional Consequences of Intragastrically Administered Ethanol in Rats as Measured by the 2‐[14C]Deoxygluocse Method

L Williams‐Hemby, LJ Porrino - Alcoholism: Clinical and …, 1997 - Wiley Online Library
The 2‐[4C] deoxyglucose (2DG) method was used to examine the effects of the acute,
intragastric (IG) administration of ethanol on rates of local cerebral glucose utilization …

Acute effects of ethanol on the transfer of nicotine and two dietary carcinogens in human placental perfusion

J Veid, V Karttunen, K Myöhänen, P Myllynen… - Toxicology letters, 2011 - Elsevier
Many mothers use, against instructions, alcohol during pregnancy. Simultaneously mothers
are exposed to a wide range of other environmental chemicals. These chemicals may also …

Nitric oxide synthase activity in the hippocampus, frontal cerebral cortex, and cerebellum of the guinea pig: ontogeny and in vitro ethanol exposure

JF Brien, JD Reynolds, MA Cunningham, AM Parr… - Alcohol, 1995 - Elsevier
Decreased nitric oxide (NO) formation, resulting from inhibition of NO synthase (NOS), may
be important in the pathogenesis of ethanol central nervous system teratogenesis. The …

Disposition of Ethanol and Activity of Hepatic and Placental Alcohol Dehydrogenase and Aldehyde Dehydrogenases in the Third‐Trimester Pregnant Guinea Pig for …

DW Clarke, NAE Steenaart… - Alcoholism: Clinical and …, 1986 - Wiley Online Library
The disposition of ethanol and its metabolite, acetaldehyde, and the activity of alcohol
dehydrogenase (ADH) and aldehyde dehydrogenases (ALOH) were determined in the third …