Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …

Highlights•Both estradiol and progesterone are essential for uterine fibroid
development.•Ovarian blockade arrests leiomyoma growth, but it has many side …

Uterine fibroids (UF), that can disrupt normal uterine function and cause significant physical
and psychological health problems, are observed in nearly 70% of women of reproductive …

Progesterone acts through the progesterone receptor to direct physiological adaption of the
uterus in preparation and completion of pregnancy. Genome-wide transcriptome and …

Background The stage, when tissues and organs are growing, is very vulnerable to
environmental influences, but it's not clear how exposure during this time causes changes to …

Uterine fibroids (UFs), also known as leiomyomas, are benign tumors of the myometrium
affecting over 70% of women worldwide, particularly women of color. Although benign, UFs …

Introduction: The progesterone receptor plays an essential role in uterine physiology and
reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a …

Uterine leiomyomas (ULs), frequent benign tumours of the female reproductive tract, are
associated with a range of symptoms and significant morbidity. Despite extensive research …

Uterine fibroids (UFs, AKA leiomyoma) are the most important benign neoplastic threat to
women's health, with costs up to hundreds of billions of health care dollars worldwide …