[HTML][HTML] Scientists' warning to humanity: microorganisms and climate change

R Cavicchioli, WJ Ripple, KN Timmis, F Azam… - Nature Reviews …, 2019 - nature.com
In the Anthropocene, in which we now live, climate change is impacting most life on Earth.
Microorganisms support the existence of all higher trophic life forms. To understand how …

Combating mosquito-borne diseases using genetic control technologies

GH Wang, S Gamez, RR Raban, JM Marshall… - Nature …, 2021 - nature.com
Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

Development of a confinable gene drive system in the human disease vector Aedes aegypti

M Li, T Yang, NP Kandul, M Bui, S Gamez, R Raban… - Elife, 2020 - elifesciences.org
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …

Evolutionary Ecology of Wolbachia Releases for Disease Control

PA Ross, M Turelli, AA Hoffmann - Annual review of genetics, 2019 - annualreviews.org
Wolbachia is an endosymbiotic Alphaproteobacteria that can suppress insect-borne
diseases through decreasing host virus transmission (population replacement) or through …

Mosquito microbiota and implications for disease control

H Gao, C Cui, L Wang, M Jacobs-Lorena, S Wang - Trends in parasitology, 2020 - cell.com
Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these
pathogens in the mosquito vector before they are transmitted to humans is an effective …

Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics

R Aguas, RM Corder, JG King, G Gonçalves… - MedRxiv, 2020 - medrxiv.org
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads, the susceptible
subpopulation declines causing the rate at which new infections occur to slow down …

Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAs

A Buchman, S Gamez, M Li… - Proceedings of the …, 2019 - National Acad Sciences
Recent Zika virus (ZIKV) outbreaks have highlighted the necessity for development of novel
vector control strategies to combat arboviral transmission, including genetic versions of the …

Heatwaves cause fluctuations in wMel Wolbachia densities and frequencies in Aedes aegypti

PA Ross, JK Axford, Q Yang, KM Staunton… - PLoS neglected …, 2020 - journals.plos.org
Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia are being released
into natural mosquito populations in the tropics as a way of reducing dengue transmission …

Wolbachia-Virus interactions and arbovirus control through population replacement in mosquitoes

TH Ant, MV Mancini, CJ McNamara… - … and Global Health, 2023 - Taylor & Francis
Following transfer into the primary arbovirus vector Aedes aegypti, several strains of the
intracellular bacterium Wolbachia have been shown to inhibit the transmission of dengue …

Host, symbionts, and the microbiome: the missing tripartite interaction

P Brinker, MC Fontaine, LW Beukeboom… - Trends in Microbiology, 2019 - cell.com
Symbiosis between microbial associates and a host is a ubiquitous feature of life on earth,
modulating host phenotypes. In addition to endosymbionts, organisms harbour a collection …