To investigate the toxicological effects of nanomaterials, experimental studies on the
absorption and accumulation in organisms are of broad interest. In the present study …

The term cancer describes a group of multifaceted diseases characterized by an intricate
pathophysiology. Despite significant advances in the fight against cancer, it remains a key …

Caenorhabditis elegans is a model organism for the study of different molecular,
biochemical, microbial and immunity-related mechanisms. In its natural habitat, C. elegans …

Abstract α-Mangostin, one of the major xanthones isolated from pericarp of mangosteen
(Garcinia mangostana Linn), exhibits a wide range of pharmacological activities, including …

Agave sisalana agro-industrial residue has considerable potential against damage
associated with oxidative stress and skin aging. This study aims to demonstrate, in vitro and …

Mitochondria are small cytoplasmic organelles whose most important function is to provide
the energy required by our cells and organism to live. To maintain an adequate …

The P23H opsin mutation is the most common cause of autosomal dominant retinitis
pigmentosa. Even though the pathobiology of the resulting retinal degeneration has been …

'Cara Cara'is a red orange (Citrus sinensis (L.) Osbeck) variety originally from Venezuela
characterized by a significantly higher and diversified carotenoid content including higher …

Oligomeric assembly of Amyloid-β (Aβ) is the main toxic species that contribute to early
cognitive impairment in Alzheimer's patients. Therefore, drugs that reduce the formation of …

Population aging is one of the largest challenges of the 21st century. As more people live to
advanced ages, the prevalence of age-related diseases and disabilities will increase …