C. elegans as a model to study PTEN's regulation and function
J Liu, ID Chin-Sang - Methods, 2015 - Elsevier
PTEN (phosphatase and tensin homolog deleted on chromosome 10) has important roles in
tumor suppression, metabolism, and development, yet its regulators, effectors, and functions …
tumor suppression, metabolism, and development, yet its regulators, effectors, and functions …
Nematode locomotion in unconfined and confined fluids
A Bilbao, E Wajnryb, SA Vanapalli, J Blawzdziewicz - Physics of Fluids, 2013 - pubs.aip.org
Nematode locomotion in unconfined and confined fluids | Physics of Fluids | AIP Publishing Skip
to Main Content Umbrella Alt Text Umbrella Alt Text Close Publishers AIP Publishing Physics …
to Main Content Umbrella Alt Text Umbrella Alt Text Close Publishers AIP Publishing Physics …
Resolving clustered worms via probabilistic shape models
The roundworm Caenorhabditis elegans is an effective model system for biological
processes such as immunity, behavior, and metabolism. Robotic sample preparation …
processes such as immunity, behavior, and metabolism. Robotic sample preparation …
Targeting the nervous system of the parasitic worm, Haemonchus contortus with quercetin
Prevalence of infection, limited choice of drugs, and emerging resistance against
contemporary medications lead to a pressing need to develop new anthelmintic drugs and …
contemporary medications lead to a pressing need to develop new anthelmintic drugs and …
Mimicking of splicing-related retinitis pigmentosa mutations in C. elegans allow drug screens and identification of disease modifiers
D Kukhtar, K Rubio-Peña, X Serrat… - Human Molecular …, 2020 - academic.oup.com
CRISPR/Cas and the high conservation of the spliceosome components facilitate the
mimicking of human pathological mutations in splicing factors of model organisms. The …
mimicking of human pathological mutations in splicing factors of model organisms. The …
C. elegans models of neuromuscular diseases expedite translational research
J Sleigh, D Sattelle - Translational Neuroscience, 2010 - degruyter.com
The nematode Caenorhabditis elegans is a genetic model organism and the only animal
with a complete nervous system wiring diagram. With only 302 neurons and 95 striated …
with a complete nervous system wiring diagram. With only 302 neurons and 95 striated …
The role of mycelium production and a MAPK-mediated immune response in the C. elegans-Fusarium model system
M Muhammed, BB Fuchs, MP Wu, J Breger… - …, 2012 - academic.oup.com
Fusariosis is an emerging infectious complication of immune deficiency, but models to study
this infection are lacking. The use of the soil nematode Caenorhabditis elegans as a model …
this infection are lacking. The use of the soil nematode Caenorhabditis elegans as a model …
C. elegans as a genetic model system to identify Parkinson's disease-associated therapeutic targets
J Vistbakka, N VanDuyn, G Wong… - CNS & Neurological …, 2012 - ingentaconnect.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-
motor symptoms and the selective loss of dopaminergic neurons. The etiology of idiopathic …
motor symptoms and the selective loss of dopaminergic neurons. The etiology of idiopathic …
[HTML][HTML] An automated phenotype-based microscopy screen to identify pro-longevity interventions acting through mitochondria in C. elegans
S Maglioni, N Arsalan, L Franchi, A Hurd… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Mitochondria are multifunctional organelles that play a central role in cellular homeostasis.
Severe mitochondrial dysfunction leads to life-threatening diseases in humans and …
Severe mitochondrial dysfunction leads to life-threatening diseases in humans and …
[HTML][HTML] Caenorhabditis elegans model for initial screening and mechanistic evaluation of potential new drugs for aging and Alzheimer's disease
Y Luo, Y Wu, M Brown, CD Link - Methods of Behavior Analysis in …, 2009 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is one of the most devastating CNS disorders of old age, which
has led to a serious public health problem. Currently about five million Americans are …
has led to a serious public health problem. Currently about five million Americans are …