[HTML][HTML] Caenorhabditis elegans model for initial screening and mechanistic evaluation of potential new drugs for aging and Alzheimer's disease
Y Luo, Y Wu, M Brown, CD Link - Methods of Behavior Analysis in …, 2009 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is one of the most devastating CNS disorders of old age, which
has led to a serious public health problem. Currently about five million Americans are …
has led to a serious public health problem. Currently about five million Americans are …
Effect of structurally related flavonoids from Zuccagnia punctata Cav. on Caenorhabditis elegans
RE D'Almeida, MR Alberto, P Morgan, M Sedensky… - Acta Parasitologica, 2015 - Springer
Abstract Zuccagnia punctata Cav.(Fabaceae), commonly called jarilla macho or pus-pus, is
being used in traditional medicine as an antiseptic, anti-inflammatory and to relieve muscle …
being used in traditional medicine as an antiseptic, anti-inflammatory and to relieve muscle …
Caenorhabditis elegans as a valuable model for studying apoptosis and autophagy in cancer development: Current insights, future directions, and challenges
Despite significant progress in the fight against cancer, cancer treatment remains a
significant public health concern and a societal burden worldwide. To develop better …
significant public health concern and a societal burden worldwide. To develop better …
Translational experimental therapeutics: The translation of laboratory‐based discovery into disease‐related therapy
K Kieburtz, CW Olanow - Mount Sinai Journal of Medicine: A …, 2007 - Wiley Online Library
In the past decade, there has been an increasing emphasis on laboratory‐based
translational research. This has led to significant scientific advances in our understanding of …
translational research. This has led to significant scientific advances in our understanding of …
Role of the ubiquitin–proteasome system in nervous system function and disease: using C. elegans as a dissecting tool
MS Baptista, CB Duarte, P Maciel - Cellular and Molecular Life Sciences, 2012 - Springer
In addition to its central roles in protein quality control, regulation of cell cycle, intracellular
signaling, DNA damage response and transcription regulation, the ubiquitin–proteasome …
signaling, DNA damage response and transcription regulation, the ubiquitin–proteasome …
[HTML][HTML] Globodera pallida, a non-transgenic invertebrate as a new model for investigating Alzheimer's disease (and other proteinopathies)?
NA Althobaiti, F Menaa, JJ Dalzell… - Neural regeneration …, 2023 - journals.lww.com
(AD): Non-human models have contributed tremendously to the understanding of AD and its
underlying pathological processes. These models have aided the investigation of the …
underlying pathological processes. These models have aided the investigation of the …
Morphology-Guided Graph Search for Untangling Objects: C. elegans Analysis
We present a novel approach for extracting cluttered objects based on their morphological
properties. Specifically, we address the problem of untangling Caenorhabditis elegans …
properties. Specifically, we address the problem of untangling Caenorhabditis elegans …
An overview of tissue engineering as an alternative for toxicity assessment
M Garrod, DY San Chau - Journal of Pharmacy & …, 2016 - journals.library.ualberta.ca
Tissue engineering is a multidisciplinary field that combines aspects of biology, material
sciences, engineering and medicine-the ultimate goal being able to fabricate replacement …
sciences, engineering and medicine-the ultimate goal being able to fabricate replacement …
Electric egg-laying: a new approach for regulating C. elegans egg-laying behaviour in a microchannel using electric field
In this paper, the novel effect of electric field (EF) on adult C. elegans egg-laying in a
microchannel is discovered and correlated with neural and muscular activities. The …
microchannel is discovered and correlated with neural and muscular activities. The …
Realgar bioleaching solution is a less toxic arsenic agent in suppressing the Ras/MAPK pathway in Caenorhabditis elegans
D Liu, D Zhi, T Zhou, Q Yu, F Wan, Y Bai, H Li - Environmental toxicology …, 2013 - Elsevier
To explore other arsenic derivatives with anticancer effects and fewer adverse effects,
realgar bioleaching solution (RBS) has been found to be a viable approach. Here we used …
realgar bioleaching solution (RBS) has been found to be a viable approach. Here we used …