Candida glabrata: Pathogenicity and Resistance Mechanisms for Adaptation and Survival

Y Hassan, SY Chew, LTL Than - Journal of Fungi, 2021 - mdpi.com
Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill
patients. It is the second most isolated Candida species associated with invasive candidiasis …

Immunity to invasive fungal diseases

A Casadevall - Annual review of immunology, 2022 - annualreviews.org
Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions

V Garcia-Bustos, MD Cabanero-Navalon, A Ruiz-Saurí… - Microorganisms, 2021 - mdpi.com
Candida auris has unprecedently emerged as a multidrug resistant fungal pathogen,
considered a serious global threat due to its potential to cause nosocomial outbreaks and …

Metallacarborane Derivatives as Innovative Anti-Candida albicans Agents

K Kubiński, M Masłyk, M Janeczko… - Journal of Medicinal …, 2022 - ACS Publications
Infections caused by Candida species have increased significantly in the past decades and
are among the leading causes of morbidity and mortality worldwide, resulting in serious …

Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts

VKA Silva, S Bhattacharya, NK Oliveira, AG Savitt… - MBio, 2022 - Am Soc Microbiol
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus
neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal …

Distinct effect of calorie restriction between congenic mating types of Cryptococcus neoformans

NK Oliveira, K Yoo, S Bhattacharya, R Gambhir… - Scientific Reports, 2024 - nature.com
Cryptococcus neoformans (Cn) is an opportunistic yeast that causes meningoencephalitis in
immunocompromised individuals. Calorie restriction (CR) prolongs Cn replicative lifespan …

Novel ABC Transporter Associated with Fluconazole Resistance in Aging of Cryptococcus neoformans

NK Oliveira, S Bhattacharya, R Gambhir, M Joshi… - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans causes meningoencephalitis in immunocompromised individuals,
which is treated with fluconazole (FLC) monotherapy when resources are limited. This can …

Superoxide dismutases in eukaryotic microorganisms: Four case studies

A de Obeso Fernandez del Valle, CQ Scheckhuber - Antioxidants, 2022 - mdpi.com
Various components in the cell are responsible for maintaining physiological levels of
reactive oxygen species (ROS). Several different enzymes exist that can convert or degrade …

With age comes resilience: how mitochondrial modulation drives age-associated fluconazole tolerance in Cryptococcus neoformans

K Yoo, S Bhattacharya, NK Oliveira, N Pereira de Sa… - mBio, 2024 - journals.asm.org
Cryptococcus neoformans (Cn) is an opportunistic fungal microorganism that causes life-
threatening meningoencephalitis. During the infection, the microbial population is …

Intra-clade Heterogeneity in Candida auris: Risk of Management

B Fayed, IK Lazreg, RB AlHumaidi, MAAA Qasem… - Current …, 2023 - Springer
Candida auris has emerged as a significant nosocomial fungal pathogen with a high risk of
pathogenicity. Since the initial detection of C. auris in 2009, it gained lots of attention with a …