Specific expression and functions of circular RNAs

S Misir, N Wu, BB Yang - Cell Death & Differentiation, 2022 - nature.com
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …

The biogenesis, biology and characterization of circular RNAs

LS Kristensen, MS Andersen, LVW Stagsted… - Nature reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes
with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by …

Translation and functional roles of circular RNAs in human cancer

M Lei, G Zheng, Q Ning, J Zheng, D Dong - Molecular cancer, 2020 - Springer
Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed
loops through backsplicing. Recent methodologies have enabled in-depth characterization …

Circular RNAs act as miRNA sponges

AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ) RNAs include a large family of noncoding (nc) RNAs that lack the 5′ or …

A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma

JL Duan, W Chen, JJ Xie, ML Zhang, RC Nie, H Liang… - Molecular cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) regulate various biological activities and
have been shown to play crucial roles in hepatocellular carcinoma (HCC) progression …

Circular RNAs and complex diseases: from experimental results to computational models

CC Wang, CD Han, Q Zhao, X Chen - Briefings in bioinformatics, 2021 - academic.oup.com
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules
with a variety of biological functions. Studies have shown that circRNAs are involved in a …

CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes

W Wu, P Ji, F Zhao - Genome biology, 2020 - Springer
Existing circular RNA (circRNA) databases have become essential for transcriptomics.
However, most are unsuitable for mining in-depth information for candidate circRNA …

[HTML][HTML] Advances in circular RNA and its applications

X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …

Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkers

M Su, Y Xiao, J Ma, Y Tang, B Tian, Y Zhang, X Li… - Molecular cancer, 2019 - Springer
Circular RNAs (circRNAs) are a class of RNA molecules with closed loops and high stability.
CircRNAs are abundantly expressed in eukaryotic organisms and exhibit both location-and …

Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …