[HTML][HTML] Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

[HTML][HTML] Methods combining genomic and epidemiological data in the reconstruction of transmission trees: a systematic review

H Duault, B Durand, L Canini - Pathogens, 2022 - mdpi.com
In order to better understand transmission dynamics and appropriately target control and
preventive measures, studies have aimed to identify who-infected-whom in actual outbreaks …

Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications

PJ Gómez-González, S Campino… - Briefings in …, 2022 - academic.oup.com
With> 1 million associated deaths in 2020, human tuberculosis (TB) caused by the bacteria
Mycobacterium tuberculosis remains one of the deadliest infectious diseases. A plethora of …

Controlling the SARS-CoV-2 outbreak, insights from large scale whole genome sequences generated across the world

J Phelan, W Deelder, D Ward, S Campino, ML Hibberd… - BioRxiv, 2020 - biorxiv.org
Background SARS-CoV-2 most likely evolved from a bat beta-coronavirus and started
infecting humans in December 2019. Since then it has rapidly infected people around the …

[HTML][HTML] Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

G Napier, AS Khan, A Jabbar, MT Khan, S Ali… - Scientific reports, 2022 - nature.com
Tuberculosis, caused by Mycobacterium tuberculosis, is a high-burden disease in Pakistan,
with multi-drug (MDR) and extensive-drug (XDR) resistance, complicating infection control …

[HTML][HTML] Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers

J Libiseller-Egger, J Phelan, S Campino… - PLoS Computational …, 2020 - journals.plos.org
Tuberculosis disease is a major global public health concern and the growing prevalence of
drug-resistant Mycobacterium tuberculosis is making disease control more difficult …

[HTML][HTML] Clusters of drug-resistant Mycobacterium tuberculosis detected by whole-genome sequence analysis of nationwide sample, Thailand, 2014–2017

D Nonghanphithak, A Chaiprasert… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Multidrug-resistant tuberculosis (MDR TB), pre-extensively drug-resistant tuberculosis (pre-
XDR TB), and extensively drug-resistant tuberculosis (XDR TB) complicate disease control …

Understanding drivers of phylogenetic clustering and terminal branch lengths distribution in epidemics of Mycobacterium tuberculosis

F Menardo - Elife, 2022 - elifesciences.org
Detecting factors associated with transmission is important to understand disease
epidemics, and to design effective public health measures. Clustering and terminal branch …

Comparing Mycobacterium tuberculosis transmission reconstruction models from whole genome sequence data

B Sobkowiak, K Romanowski, I Sekirov… - Epidemiology & …, 2023 - cambridge.org
Genomic epidemiology is routinely used worldwide to interrogate infectious disease
dynamics. Multiple computational tools exist that reconstruct transmission networks by …

Transmission characteristics in Tuberculosis by WGS: nationwide cross-sectional surveillance in China

D Liu, F Huang, Y Li, L Mao, W He, S Wu… - Emerging Microbes & …, 2024 - Taylor & Francis
China, with the third largest share of global tuberculosis cases, faces a substantial challenge
in its healthcare system as a result of the high burden of multidrug-resistant and rifampicin …