Bioelectric pharmacology of cancer: a systematic review of ion channel drugs affecting the cancer phenotype
K Kofman, M Levin - Progress in Biophysics and Molecular Biology, 2024 - Elsevier
Cancer is a pernicious and pressing medical problem; moreover, it is a failure of
multicellular morphogenesis that sheds much light on evolutionary developmental biology …
multicellular morphogenesis that sheds much light on evolutionary developmental biology …
[HTML][HTML] Targeting T regulatory (Treg) cells in immunotherapy-resistant cancers
P Spiliopoulou, P Kaur, T Hammett… - Cancer Drug …, 2024 - ncbi.nlm.nih.gov
Primary or secondary (ie, acquired) resistance is a common occurrence in cancer patients
and is often associated with high numbers of T regulatory (T reg) cells (CD4+ CD25+ …
and is often associated with high numbers of T regulatory (T reg) cells (CD4+ CD25+ …
[HTML][HTML] Structural Changes, Biological Consequences, and Repurposing of Colchicine Site Ligands
F Montecinos, DL Sackett - Biomolecules, 2023 - mdpi.com
Microtubule-targeting agents (MTAs) bind to one of several distinct sites in the tubulin dimer,
the subunit of microtubules. The binding affinities of MTAs may vary by several orders of …
the subunit of microtubules. The binding affinities of MTAs may vary by several orders of …
Drug repurposing as a potential source of innovative therapies in cervical cancer
S Paul, I Boere, P Pantziarka, S Chopra… - International Journal of …, 2022 - ijgc.bmj.com
Objective Drug repurposing is an alternative development pathway that utilizes the
properties of drugs approved for other diseases and builds on available safety and …
properties of drugs approved for other diseases and builds on available safety and …
[PDF][PDF] Drug repurposing as a potential source of innovative therapies in cervical cancer
I Rica Capistrano, S Paul, I Boere, P Pantziarka… - 2022 - pure.eur.nl
Objective Drug repurposing is an alternative development pathway that utilizes the
properties of drugs approved for other diseases and builds on available safety and …
properties of drugs approved for other diseases and builds on available safety and …
Using ML to repurpose FDA drugs for the treatment of Diabetic Cardiomyopathy
V Aravind, A Kumar - 2023 - chemrxiv.org
PARP-1 (Poly ADP Ribose polymerase) functions to repair damage to DNA and is
implicated in a variety of diseases including Diabetic Cardiomyopathy (DCM). Unfortunately …
implicated in a variety of diseases including Diabetic Cardiomyopathy (DCM). Unfortunately …
[PDF][PDF] Repurposing Drugs for Cancer Therapeutics
S Srivastava - researchgate.net
Repurposing of drugs for anti-cancer indications are now being done to increase candidate
drug pool. Many of the drugs out of shelves can be used to target cancer hallmark …
drug pool. Many of the drugs out of shelves can be used to target cancer hallmark …