GWAS for genetics of complex quantitative traits: Genome to pangenome and SNPs to SVs and k‐mers

PK Gupta - BioEssays, 2021 - Wiley Online Library
The development of improved methods for genome‐wide association studies (GWAS) for
genetics of quantitative traits has been an active area of research during the last 25 years …

Runs of homozygosity in the Italian goat breeds: Impact of management practices in low-input systems

M Cortellari, A Bionda, A Negro, S Frattini… - Genetics Selection …, 2021 - Springer
Background Climate and farming systems, several of which are considered as low-input
agricultural systems, vary between goat populations from Northern and Southern Italy and …

Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheep

J Wang, G Hua, G Cai, Y Ma, X Yang, L Zhang… - Journal of Animal …, 2023 - Springer
Background Wool fibers are valuable materials for textile industry. Typical wool fibers are
divided into medullated and non-medullated types, with the former generated from primary …

Copy number variants in genomes of local sheep breeds from Russia

AV Igoshin, TE Deniskova, AA Yurchenko… - Animal …, 2022 - Wiley Online Library
Copy number variants (CNVs) are genomic structural variations that contribute to many
adaptive and economically important traits in livestock. In this study, we detected CNVs in …

Genome-wide analysis of CNVs in three populations of Tibetan sheep using whole-genome resequencing

L Hu, L Zhang, Q Li, H Liu, T Xu, N Zhao, X Han… - Frontiers in …, 2022 - frontiersin.org
Copy number variation (CNV), an important source of genomic structural variation, can
disturb genetic structure, dosage, regulation and expression, and is associated with …

Comparative signatures of selection analyses identify loci under positive selection in the Murrah Buffalo of India

SK Tyagi, A Mehrotra, A Singh, A Kumar, T Dutt… - Frontiers in …, 2021 - frontiersin.org
India is home to a large and diverse buffalo population. The Murrah breed of North India is
known for its milk production, and it has been used in breeding programs in several …

High-density SNP markers elucidate the genetic divergence and population structure of Noticiana sheep breed in the Mediterranean context

G Chessari, A Criscione, M Tolone… - Frontiers in Veterinary …, 2023 - frontiersin.org
Among livestock species, sheep have played an early major role in the Mediterranean area.
Italy has a long history of sheep breeding and, despite a dramatic contraction in numbers …

The identification of a novel SNP in the resistin (RETN) gene associated with growth traits in Karakul and Awassi sheep

TRS Aljubouri, MBS Al-Shuhaib - Tropical animal health and production, 2023 - Springer
Resistin is one of the most important adipocytokines in mammalian cells due to its
involvement in insulin resistance, obesity, and autoimmune diseases. Resistin is encoded …

One intron variant in the oocyte expressed protein (OOEP) gene is associated with twinning rate, prolificacy, and several body measurement traits in Awassi ewes

NM Khazaal, HFK Alghetaa, AH Alkhammas… - Small Ruminant …, 2023 - Elsevier
Awassi breed is an important sheep in the Middle East, but its lower twinning potential is a
limitation against improvement. Due to the dynamic role of oocyte-expressed protein (OOEP) …

Molecular Characterization of the Antiviral Properties of the Small HERC Family of Proteins

E Paparisto - 2023 - ir.lib.uwo.ca
Although viruses are obligate intracellular parasites, they have their own evolutionary
trajectory, their genomes are in a constant battle to overcome the defenses of the host. This …