Abstract Background Mesenchymal stem cells (MSCs) hold great potential as a therapy for
stroke and have previously been shown to promote recovery in preclinical models of …

Ischemic stroke is one of the leading causes of death and disability. Ischemia triggers a
cascade of events leading to cell death and cerebral infarction. Mesenchymal stem cell …

Stroke remains a major unmet clinical need that warrants novel therapies. Following an
ischemic insult, the cerebral vasculature secretes inflammatory molecules, creating the …

Unlike the terminally differentiated somatic cells, stem cells are characterized by their
unlimited, undifferentiated self-renewal, and differentiation potential to adopt diverse …

Ischemic stroke is a devastating central nervous disease. Despite extensive research in to
this area, few innovative neuroprotective treatments have been presented. 7 …

Cerebral ischaemia is the most common cause of impaired brain function. Biologically active
peptides represent potential drugs for reducing the damage that occurs after ischaemia. The …

Background: Ischemic stroke is a serious public health problem. Despite extensive
researches focusing on the area, little is known about novel treatments. Objective: In this …

As major active ingredients of the traditional Chinese medicine motherwort, stachydrine and
leonurine were found to have protective effects against cerebral ischemia. However, their …

Fetal alcohol spectrum disorders (FASD) are prevalent neurodevelopmental disorders.
Genetics have been shown to have a role in the severity of alcohol's teratogenic effects on …

Ischemic stroke is one of the most vital causes of high neurological morbidity and mortality in
the world. Preconditioning exercise is considered as the primary prevention of stroke to …